On-Chip Pre-Treatment of Biological Samples for the Isolation of Adipose Stem Cells (ASCs)

M. Valette, Mathias Bouguelmouna, M. Mariotte, R. Courson, Marie-Charline Blatché, A. Girousse, C. Sengenès, K. Reybier, A. Gué
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Abstract

This study presents the development of an original 2-steps Lab-on-chip that aims at isolating Adipose Stem Cells (ASCs), cells of considerable interest for regenerative medicine, from complex biological samples. Based on hydrodynamic filtration, the device pre-isolates ASCs by removing cells with a diameter below 10µm such as red blood cells or lymphocytes.
分离脂肪干细胞生物样品的芯片前处理
本研究提出了一种原始的2步芯片实验室,旨在从复杂的生物样品中分离脂肪干细胞(ASCs),这是再生医学中非常感兴趣的细胞。基于水动力过滤,该装置通过去除直径小于10µm的细胞(如红细胞或淋巴细胞)来预分离ASCs。
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