Oral Inverted Ductal Papilloma: Report of a Case with Immunohistochemical Study

Abstract

Oral inverted ductal papilloma (IDP) is a very uncommon lesion of minor salivary gland origin. Forty five cases have been reported in the literature. We describe a case of IDP developed as an asymptomatic submucosal mass in the hard palate of a middle-aged woman. Excisional biopsy was performed, and ten months of patient's follow-up showed no evidence of recurrence. The major portion of the tumour was made up of proliferating configurations containing epi- dermoid cells. Some microcysts and crypts were seen. Immunohistochemical analysis of the present case supports the hy- pothesis that IDP arises from excretory duct cells.