Psoralen with ultraviolet A‐induced apoptosis of cutaneous lymphoma cell lines is augmented by type I interferons via the JAK1–STAT1 pathway

Abstract

Photochemotherapy with psoralen and ultraviolet A (PUVA), with or without adjuvant interferon‐α (IFN‐α), is a first‐line therapy for early‐stage mycosis fungoides and other forms of cutaneous T‐cell lymphoma (CTCL). However, the mechanism by which PUVA with IFN‐α work in CTCL is poorly understood.