Extensive Leptomeningeal Spreading of Ependymoma in an Adult: Case Report and Literature Review.

Joonseo Kang, Kwon Woo Lee, Yeongu Chung, Yusam Won, Je Beom Hong
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Abstract

Ependymoma is a rare adult tumor that originates from ependymal cells of the central nervous system, primarily occurring in the cerebral ventricles or the central canal of the spinal cord. In this paper, we report a case of extensive leptomeningeal seeding of ependymoma of a 39-year-old male patient, in whom the tumor was found incidentally after head trauma. The MRI exhibited diffuse leptomeningeal infiltrative lesions along with bilateral multiple cerebral sulci, basal cisterns, cerebellopontine angle, cerebellar folia. It also showed multinodular enhancing T1 low T2 high signal intensity lesions along the whole spinal cord. After the tumor biopsy at right temporal lesion, pathologic diagnosis was classic ependymoma (WHO grade 2). The patient has undergone radiation therapy and chemotherapy, and is currently maintaining a stable condition two years after surgery. This report suggests that when considering the differential diagnosis of extensive lesions both in the intracranial and intraspinal space, ependymoma should also be considered.

成人室管膜瘤广泛的脑膜扩散:1例报告及文献复习。
室管膜瘤是一种罕见的成人肿瘤,起源于中枢神经系统的室管膜细胞,主要发生在脑室或脊髓中央管。在这篇文章中,我们报告一个39岁的男性患者,在头部外伤后偶然发现了广泛的室管膜瘤。MRI表现为弥漫性脑脊膜浸润性病变,伴双侧多脑沟、基底池、桥小脑角、小脑叶。它还显示沿整个脊髓的多结节增强T1低T2高信号强度病变。右侧颞叶病变肿瘤活检后,病理诊断为典型室管膜瘤(WHO分级2级)。患者接受放疗和化疗,术后2年病情稳定。本报告提示,在考虑颅内和椎管间隙广泛病变的鉴别诊断时,也应考虑室管膜瘤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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