Clinical Assessment Interview for Negative Symptoms (CAINS): A Systematic Review of Measurement Properties.

IF 5.3 1区医学 Q1 PSYCHIATRY

Schizophrenia Bulletin Pub Date : 2024-07-27 DOI:10.1093/schbul/sbad137

Sophia Wehr, Lucia Weigel, John Davis, Silvana Galderisi, Armida Mucci, Stefan Leucht

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引用次数: 0

Abstract

Background and hypothesis: Negative symptoms are very important for the overall loss of functioning observed in patients with schizophrenia. There is a need for valid tools to assess these symptoms.

Study design: We used the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) systematic review guideline to evaluate the quality of the clinical assessment interview for negative symptoms (CAINS) as a clinician-rated outcome measurement (ClinROM).

Study results: The search strategy resulted in the retrieval of 13 articles, 11 of which were included in this evaluation. In terms of risk of bias, most articles reported on measures of internal consistency and construct validity, which were overall of good quality. Structural validity, reliability, measurement error, and cross-cultural validity were reported with less than optimum quality. There was a risk of bias in ClinROM development. According to the updated criteria of good measurement properties, structural validity, internal consistency, and reliability showed good results. In contrast, hypothesis testing was somewhat poorer. Results for cross-cultural validity were indeterminate. According to the updated GRADE approach from the COSMIN group the scale received a moderate grade.

Conclusions: The COSMIN standard allows a judgment of the CAINS as an instrument with the potential to be recommended for use, but which requires further research to assess its quality, in particular in the domains of content validity, internal consistency, and cross-cultural validity.

查看原文本刊更多论文

阴性症状临床评估访谈(CAINS):测量特性的系统回顾。

背景与假设:阴性症状对精神分裂症患者整体功能丧失非常重要。需要有效的工具来评估这些症状。研究设计:我们使用基于共识的健康测量工具选择标准(COSMIN)系统评价指南来评价阴性症状(CAINS)作为临床评价结果测量(ClinROM)的临床评估访谈的质量。研究结果:检索策略共检索到13篇文献，其中11篇纳入本次评价。在偏倚风险方面，大多数文章报告了内部一致性和结构效度的测量，总体质量良好。结构效度、信度、测量误差和跨文化效度均低于最佳质量。在ClinROM开发中存在偏倚风险。根据更新的测量性能标准，结构效度、内部一致性和信度显示出良好的效果。相比之下，假设检验就差一些。跨文化效度的结果不确定。根据COSMIN组更新的GRADE方法，量表获得中等等级。结论:COSMIN标准允许对CAINS作为一种有可能被推荐使用的工具进行判断，但这需要进一步的研究来评估其质量，特别是在内容有效性、内部一致性和跨文化有效性方面。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Schizophrenia Bulletin 医学-精神病学

CiteScore

11.40

自引率

6.10%

发文量

163

审稿时长

4-8 weeks

期刊介绍： Schizophrenia Bulletin seeks to review recent developments and empirically based hypotheses regarding the etiology and treatment of schizophrenia. We view the field as broad and deep, and will publish new knowledge ranging from the molecular basis to social and cultural factors. We will give new emphasis to translational reports which simultaneously highlight basic neurobiological mechanisms and clinical manifestations. Some of the Bulletin content is invited as special features or manuscripts organized as a theme by special guest editors. Most pages of the Bulletin are devoted to unsolicited manuscripts of high quality that report original data or where we can provide a special venue for a major study or workshop report. Supplement issues are sometimes provided for manuscripts reporting from a recent conference.