Bacterial cellulose: A smart biomaterial for biomedical applications

IF 0.7 4区材料科学 Q4 METALLURGY & METALLURGICAL ENGINEERING

International Journal of Materials Research Pub Date : 2023-08-17 DOI:10.1557/s43578-023-01116-4

Ashutosh Pandey, M. Singh, Annika Singh

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Abstract

The escalating curiosity in bacterial cellulose (BC) due to exceptional attributes such as purity, biodegradability, non-toxicity, porous fibrillar structure, and high water retention potential expand its applications to tissue engineering, controlled drug delivery, and cosmetics. BC has proved highly prospective to be used to manufacture innovative wound care solutions, drug carriers and delivering complexes. The drug-carrying BC found enormous applications in dental therapies, wound care, and scare-free wound management. Various degradation techniques of BC under antibiotic environments and physiological conditions offer different advantages in drug design. The drug loading capacity of BC can be increased by in situ modifications of its fibrillar network. The BC-based scaffolds compounded with other materials such as nanopolymers have explored new frontiers for BC applications in auspicious biomedicinal product developments. BC can accommodate different nanoparticles, biomaterials, synthetic materials, carbon materials, and plant extracts, which allows using BC in various biomedical and cosmetic products. Graphical abstract

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细菌纤维素:用于生物医学应用的智能生物材料

细菌纤维素(BC)由于其纯度、可生物降解性、无毒性、多孔纤维结构和高保水潜力等特殊特性，使其在组织工程、药物输送控制和化妆品等领域的应用不断扩大。BC已被证明具有很高的前景，用于制造创新的伤口护理解决方案，药物载体和输送复合物。携带药物的BC在牙科治疗、伤口护理和无惊吓伤口管理方面有巨大的应用。各种抗生素环境和生理条件下BC的降解技术在药物设计中具有不同的优势。BC的载药能力可以通过原位修饰其纤维网络来增加。BC基支架与其他材料如纳米聚合物复合，为BC在吉祥生物医药产品开发中的应用开辟了新的领域。BC可以容纳不同的纳米颗粒、生物材料、合成材料、碳材料和植物提取物，这使得BC可以在各种生物医学和化妆品中使用。图形抽象

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来源期刊

International Journal of Materials Research 工程技术-冶金工程

CiteScore

1.30

自引率

12.50%

发文量

119

审稿时长

6.4 months

期刊介绍： The International Journal of Materials Research (IJMR) publishes original high quality experimental and theoretical papers and reviews on basic and applied research in the field of materials science and engineering, with focus on synthesis, processing, constitution, and properties of all classes of materials. Particular emphasis is placed on microstructural design, phase relations, computational thermodynamics, and kinetics at the nano to macro scale. Contributions may also focus on progress in advanced characterization techniques. All articles are subject to thorough, independent peer review.