Hypotheses for isotretinoin mechanisms of action in acne treatment

Abstract

Currently, the problem of acne does not lose its relevance not only among adolescents, but also in adult women and men. One of the most effective drugs in the treatment of severe and resistant forms of acne are isotretinoin preparations, i.e. systemic retinoids, the instructions for which do not indicate the mechanism of action. The purpose of the work: to consider the hypotheses of the mechanism of action of systemic retinoids on various pathogenetic acne factors.