The Long-Term Effects of Inhaled Corticosteroid Treatment in Children With Asthma:

Abstract

Inhaled corticosteroids (ICS) are the preferred method of therapy for persistent asthma in children, providing the most effective anti-inflammatory treatment available. This article defines treatment with ICS in children and discusses current research findings related to the long-term side effects and safety concerns related to ICS therapy in children with asthma. Major safety concerns associated with long-term treatment with ICS include the potential effect on adrenal function, the inhibition of linear growth and growth velocity, osteoporosis, and ocular disorders. This article describes side effects associated with ICS and implications in pediatric primary care.