The anti–cancer nano drug delivery 13C–edited/13C–filtered transferred dynamic 15N{1H} NOE measurements for studying DNA/RNA interactions with short non–linear motifs: A modern tool for studying DNA/RNA dynamics in gum cancer cells
{"title":"The anti–cancer nano drug delivery 13C–edited/13C–filtered transferred dynamic 15N{1H} NOE measurements for studying DNA/RNA interactions with short non–linear motifs: A modern tool for studying DNA/RNA dynamics in gum cancer cells","authors":"A. Heidari, R. Gobato","doi":"10.15761/DOMR.1000365","DOIUrl":null,"url":null,"abstract":"In the current work, the anti–cancer Nano drug delivery 13C–edited/13C–filtered transferred dynamic 15N{1H} NOE measurements for studying DNA/RNA interactions with short non–linear motifs as a modern tool for studying DNA/RNA dynamics in gum cancer cells are studied. While improvements in screening have enabled the early diagnoses of many gum cancers, the significant number of diagnoses that eventually lead to death (~20% at 15 years) provide the primary impetus for advances in surgical intervention.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"25 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"11","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dental, Oral and Maxillofacial Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15761/DOMR.1000365","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 11
Abstract
In the current work, the anti–cancer Nano drug delivery 13C–edited/13C–filtered transferred dynamic 15N{1H} NOE measurements for studying DNA/RNA interactions with short non–linear motifs as a modern tool for studying DNA/RNA dynamics in gum cancer cells are studied. While improvements in screening have enabled the early diagnoses of many gum cancers, the significant number of diagnoses that eventually lead to death (~20% at 15 years) provide the primary impetus for advances in surgical intervention.