Epidermal Langerhans cells resistance to solar‐simulated radiation in actinic prurigo patients with low minimal erythema dose

Abstract

Actinic prurigo is a chronic photodermatosis of unclear pathogenesis. Epidermal Langerhans cell resistance to migration after ultraviolet radiation exposure has been proposed as a possible mechanism, as occurs in polymorphic light eruption patients. The purpose of this study was to evaluate the effect of solar‐simulated radiation (SSR) on epidermal Langerhans cells in the uninvolved skin of actinic prurigo patients.