Extraction and Characterization of Proanthocyanidins from Grape Seeds

Sean X. Liu, Elizabeth White
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引用次数: 44

Abstract

Grape seed contains many polyphenolic compounds that have potential health-promoting benefits. Among the- se compounds are proanthocyanidins, also known as condensed tannins, which is a class of flavanols. The basic structural building blocks of flavanols are polyhydroxyflavan-3-ol units linked together by C-C bonds. They are widely distributed in plants but grape seed has very high contents. This study examined extraction and purification technologies for obtain- ing proanthocyanidins from grape seeds and analytical methods and tools for characterizing them. Proanthocyanidins are polyphenolic compounds that can be found in the plant physiology of several plant species, are mainly concentrated in tree barks and outer skins of seeds. Grape seeds are one of the richest sources of proanthocyanidins (2). Public awareness of the antioxidant and free radical-scavenging abilities of these phenolic com- pounds results largely from the potential of these compounds to increase human health in many ways. Reductions in cardi- ovascular disease, cerebrovascular diseases, and cancer mor- tality are just some of the noticeable examples associated with these phenolic compounds (3-5). Recent advances in the field of nutraceuticals have shown that the compounds found in grapes exhibit even more benefits than initially be- lieved. This paper aims at reviewing these compounds found in the anatomy of the grape seeds and current methods of separation and characterization of proanthocyandins.
葡萄种子中原花青素的提取及性质研究
葡萄籽含有许多多酚类化合物,对健康有潜在的促进作用。在这些化合物中有原花青素,也被称为缩合单宁,它是黄烷醇的一类。黄烷醇的基本结构单元是由C-C键连接在一起的多羟基黄烷-3-醇单元。它们在植物中分布广泛,但葡萄籽的含量很高。本文研究了从葡萄籽中提取原花青素的提取纯化工艺,以及对原花青素进行表征的分析方法和工具。原花青素是多种植物生理中存在的多酚类化合物,主要集中在树皮和种子外皮中。葡萄籽是原花青素最丰富的来源之一(2)。公众对这些酚类化合物的抗氧化和清除自由基能力的认识主要源于这些化合物在许多方面促进人体健康的潜力。减少心血管疾病、脑血管疾病和癌症发病率只是与这些酚类化合物相关的一些显著例子(3-5)。营养保健品领域的最新进展表明,葡萄中发现的化合物比最初认为的更有益处。本文综述了葡萄籽中发现的原花青素类化合物及其分离鉴定方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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