Aktivitas Antibakteri Ekstrak Bunga Telang (Clitoria ternatea L.) terhadap Bakteri Patogen

Febrianti Febrianti, A. Widyasanti, Siti Nurhasanah
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引用次数: 0

Abstract

Penyakit manusia dapat disebabkan oleh kontribusi bakteri yang menyebabkan infeksi. Penggunaan tanaman sebagai pengobatan tradisional memainkan peran penting dalam kesehatan karena dianggap sebagai salah satu sumber yang paling menjanjikan untuk penemuan agen antimikroba baru yang minim efek samping. Bunga telang mulai dilirik masyarakat Indonesia sebagai bunga dengan berbagai macam manfaat bagi kesehatan manusia salah satunya sebagai antibakteri, namun sayangnya belum diketahui seberapa jauh manfaat tersebut. Penelitian ini bertujuan untuk mengeksplorasi kandungan senyawa dan studi antibakteri ekstrak bunga telang menggunakan beberapa pelarut bersama dengan penilaian kritis terhadap potensinya di masa depan. Metode penelitian dilakukan dengan metode penelusuran literatur. Senyawa metabolit sekunder yang ditemukan pada ekstrak bunga telang seperti flavonoid, alkaloid, fenol, saponin dan tanin bertanggungjawab atas aktivitas antibakteri. Ekstrak bunga telang terbukti memberikan aktivitas antibakteri terhadap beberapa bakteri patogen penyebab konjungtivis, keracunan makanan, infeksi saluran kemih, infeksi kulit dan kerusakan gigi. Bakteri patogen seperti P. aeruginosa, E. coli, dan S. aureus berhasil dihambat pertumbuhannya dengan nilai Diameter Daya Hambat (DDH) 8 ‒ 26 mm. Aktivitas antibakteri yang dimilikinya dipengaruhi oleh pelarut yang digunakan, ekstrak metanol dengan konsentrasi 200 mg/mL memberikan aktivitas antibakteri yang paling kuat terhadap P. aeruginosa dengan nilai DDH 26 mm yang tergolong penghambatan kategori kuat. Hal ini membuktikan ekstrak bunga telang memiliki potensi untuk dikembangkan sebagai antibakteri alami.Antibacterial Activity of Clitoria ternatea L. Extract against Pathogenic Bacteria. Human disease can be caused by bacteria that cause infections. The use of plants as traditional has played an important role in health because it is considered as one of the most promising sources for the discovery of new antimicrobial agents with minimal side effects. Recently, C. ternatea has attracted much attention for Indonesian people as a flower with various benefits for human health, one of which is as an antibacterial. However, how far these benefits are still being investigated. For this reason, this study aims to explore the compound content and antibacterial studies of C. ternatea extract using several solvents along with a critical assessment of its potential in the future. The research method used was the literature search method. Secondary metabolite compounds found in C. ternatea extracts, such as flavonoids, alkaloids, phenols, saponins, and tannins, are responsible for the antibacterial activity. C. ternatea extract has antibacterial activity against several pathogenic bacteria that cause conjunctivitis, food poisoning, urinary tract infections, skin infections, and tooth decay. Pathogenic bacteria such as P. aeruginosa, E. coli, and S. aureus were inhibited with an inhibition zone value of 8 ‒ 26 mm. Its antibacterial activity is influenced by the solvent used, methanol extract with a concentration of 200 mg/mL gave the strongest activity against P. aeruginosa with an inhibition zone of 26 mm, classified as a strong inhibitory category. This proves that the C. ternatea extract has the potential to be further developed as a natural antibacterial agent.
用于病原体的提取物的抗菌活性
人类的疾病可能是由导致感染的细菌的影响引起的。使用植物作为传统药物对健康起着重要作用,因为它被认为是发现新抗菌素制剂几乎没有副作用的最有前途的来源之一。印度公众开始将铁锹开花作为一种对人类健康有好处的花,其中一种是抗菌的,但不幸的是,目前还不清楚这种花能带来多大的好处。本研究旨在探讨藤壶花提取物的化合物含量和对抗菌提取物的研究,使用一些溶剂和对其未来潜力的批判性评估。研究方法是通过文献查找方法进行的。在银泰提取物中发现的次生代谢物质,如黄酮、生物碱、苯酚、苯酚和单宁对抗菌活动负责。telang证明抗菌活动花提取物对一些病原体konjungtivis,食物中毒的原因,泌尿系感染、皮肤感染和蛀牙。这些病原体如P .胞菌、大肠杆菌和S .奥里斯成功生长受抑制的直径资源价值等等(DDH) 8—26毫米。活动受到的抗菌功能,使用的溶剂提取甲醇浓度为200 mg / mL对P .胞菌提供了最强大的抗菌活性被抑制的DDH价值26毫米级。这证明telang花提取物有潜力开发天然抗菌。抑制抑制细菌病原Clitoria terna茶. Extract against病原细菌。人类疾病可能是由导致感染的细菌引起的。像传统的植物一样,利用植物在健康中发挥了一个重要的作用,因为它被认为是发现新抗菌素资产的最令人承诺的资源之一,其影响最少。最近,印尼人对他们的健康有着各种各样的好处,其中之一是防菌。但是,这些福利机构仍在调查中。出于这个原因,这项研究允许探索C. ternatea extract使用的某些条款solvents及其在未来潜在的批判评估。过去的研究方法是阅读方法。二次代谢化合物发现在C.三种提取中,因此像鞭毛、生物碱、表皮、表单、表单和鞣质一样,对抗菌行为负责。C. ternatea extract有抗菌活性对某些病原细菌的抗菌活性,食物中毒,尿道感染,皮肤感染和牙齿病变。杆菌是被8 - 26毫米抑制抑制的。它的抗菌活性已被solvent所影响,甲烷以200毫克的浓度释放,用一种非常强的抑制区抑制了对P。这些证据表明,C. ternatea extract有可能更远发展为一种天然抗细菌剂。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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