Split-face comparison of the efficacy of picosecond 532 nm Nd:YAG laser and Q-switched 755 nm Alexandrite laser for treatment of freckles

IF 1.2 4区医学 Q3 DERMATOLOGY

Journal of Cosmetic and Laser Therapy Pub Date : 2022-04-10 DOI:10.1080/14764172.2022.2049311

Shao-yin Ma, Ye-Qing Gong, Wen- Jun Zhang, B. Liang, Yue-Ming Li, Zhi Xie, Huilan Zhu

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引用次数: 0

Abstract

ABSTRACT To date, there has been little study of comparison between picosecond 532 nm laser and 755 nm Q-switched Alexandrite lasers in the treatment of freckles. To evaluate the efficacy and safety of picosecond 532 nm laser (PS 532) and 755 nm Q-switched Alexandrite laser (QSAL) for treatment of freckles in a split-face manner. Eighteen patients with freckles were enrolled in the study. The right and left sides of their faces were randomly assigned to either a QSAL-treated group or PS 532-treated group. The degree of pain, satisfaction with the results, and adverse events associated with the laser treatment were evaluated using a questionnaire. All of the patients were followed up at 4 and 12 weeks after one treatment session. Among the 18 patients, PS 532 was found to be associated with less pain (3.56 ± 2.431) than QSAL (3.94 ± 1.893), but the difference was not statistically significant. The curative effect and satisfaction associated with 755 nm Q-switched Alexandrite laser was greater than that of picosecond 532 nm laser (P < .001). Both picosecond 532 nm laser and QSAL are effective in the treatment of freckles, and QSAL has a greater rate of satisfaction and curative effect.

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皮秒532 nm Nd:YAG激光与调q 755 nm紫翠石激光治疗雀斑疗效的裂面比较

迄今为止，比较皮秒532 nm激光和755 nm调q亚历山大宝石激光治疗雀斑的研究很少。评价皮秒532 nm激光(PS 532)和755 nm调q亚历山大宝石激光(QSAL)治疗裂脸雀斑的疗效和安全性。18名雀斑患者参加了这项研究。他们的左右脸被随机分配到qsal治疗组或PS 532治疗组。疼痛程度、对结果的满意度和与激光治疗相关的不良事件通过问卷调查进行评估。所有患者在一次治疗后的第4周和第12周进行随访。在18例患者中，PS 532与QSAL(3.94±1.893)的疼痛相关性(3.56±2.431)较QSAL(3.94±1.893)低，但差异无统计学意义。755 nm调q紫翠石激光治疗的疗效和满意度高于皮秒532 nm激光治疗(P < 0.001)。皮秒532 nm激光和QSAL均能有效治疗雀斑，且QSAL的满意率和疗效更高。

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来源期刊

Journal of Cosmetic and Laser Therapy DERMATOLOGY-SURGERY

CiteScore

2.50

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： A unique journal that focuses on the application of cosmetic laser and light therapies on the skin. The Journal of Cosmetic & Laser Therapy provides a forum for stimulating and up-to-date studies demonstrating the wide range of therapeutic options for clinicians and surgeons involved in cosmetic and dermatological treatment. The journal is aimed at dermatologists, cosmetic surgeons, plastic and facial plastic surgeons, oculoplastic surgeons and all those interested in the rapidly expanding field of cosmetic and laser therapy. Features include: -Cosmetic surgery, including facial rejuvenation, hair removal and skin resurfacing -Use of lasers and other light sources for cosmetic and dermatological treatment -Applications of peeling agents, fillers, injectables, implants and other cosmetic modalities -Topical treatments -Practical tips and safety issues