Histopathological examination after appendectomy: Neoplastic lesions

Abstract

Appendiceal neoplasms include rare tumor formations, whose treatment ranges from an appendectomy, hemicolectomy, and chemotherapeutic agents for benign or malignant lesions. In this study, we aimed to evaluate appendiceal neoplastic lesions according to the literature on histological subgroups. A review was performed on 2.124 patients who had undergone appendectomy between January 2017 and December 2021. Patients were evaluated retrospectively according to their demographic, clinical, radiological, and histopathological characteristics. In the histopathological evaluation of the 23 (1.06%) patients, who were included in the study upon the detection of the appendiceal neoplastic lesion, sessile serrated adenoma was observed in 7 patients, low-grade appendiceal mucinous neoplasm (LAMN) in 6 patients, mucinous adenocarcinoma in 4 patients, signet ring cell mucinous adenocarcinoma in 1 patient, neuroendocrine tumor (NET) in 4 patients, and tubulovillous adenoma in 1 patient. Appendiceal neoplasms are generally asymptomatic; therefore, pathological examination results should be carefully evaluated after appendectomy, and it should be remembered that appendectomy is not always sufficient alone.