An Observational Study between Intrathecal Fentanyl and Butorphanol with Low Dose Bupivacaine to Facilitate Early Ambulation in Perineal Surgeries

M. Mehta, S. Jha, P. Shah
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Abstract

Background: Neuraxial opioids are widely used with local anaesthetics as they allow lower dose of local anaesthetics while providing adequate anaesthesia and faster recovery from spinal anaesthesia because of their sympathetic and motor nerve sparing activities. In the last few years the number of surgeries performed on an ambulatory basis has increased worldwide because of many advantages like short hospital stay, less chance of wound infection and less chances of deep vein thrombosis.Methods: 64 patients of ASA- I or II of either gender who underwent perineal surgeries were divided into two groups of 32 each:- Group BF patients received 1ml of 0.5% hyperbaric bupivacaine with 20µg fentanyl(0.4ml) and Group BB patients received 1ml of 0.5% hyperbaric bupivacaine with 200µg butorphanol(0.2ml) and normal saline(0.2ml).Patients were observed for onset of sensory and motor blockade, duration of sensory and motor blockade, duration of analgesia and time to unassisted ambulation. There was no difference in onset of sensory and motor blockade between the two groups(P> 0.005).Patients receiving butorphanol had statistically significantly longer duration of sensory and motor blockade and duration of analgesia than fentanyl(p-0.001).Patients receiving fentanyl were observed to ambulate unassisted significantly early compared to butorphanol (p-0.001).Conclusion: Patients receiving intrathecal fentanyl 20µg can ambulate earlier compared to patients receiving butorphanol 200µg when used as an adjuvant with low dose hyperbaric bupivacaine 0.5% without any complication.
芬太尼与布托啡诺联合小剂量布比卡因促进会阴手术早期活动的观察研究
背景:轴向阿片类药物被广泛应用于局部麻醉,因为它们可以在提供足够麻醉的同时减少局部麻醉剂量,并且由于它们的交感神经和运动神经保留活动而使脊髓麻醉恢复更快。在过去的几年里,由于住院时间短、伤口感染的机会少、深静脉血栓形成的机会少等许多优点,在全球范围内进行的门诊手术数量有所增加。方法:将行会阴手术的ASA- I型或II型患者64例分为两组,每组32例:BF组患者给予0.5%高压布比卡因1ml加20µg芬太尼(0.4ml), BB组患者给予0.5%高压布比卡因1ml加200µg布托啡诺(0.2ml)和生理盐水(0.2ml)。观察患者感觉和运动阻断的发生、感觉和运动阻断的持续时间、镇痛的持续时间和独立活动的时间。两组感觉和运动阻滞的发生时间差异无统计学意义(P> 0.005)。布托啡诺患者的感觉和运动阻断持续时间及镇痛持续时间均长于芬太尼,差异有统计学意义(p < 0.001)。与布托啡诺相比,接受芬太尼治疗的患者在没有辅助的情况下明显更早地行走(p-0.001)。结论:鞘内注射芬太尼20µg的患者与布托啡诺200µg的患者相比,与0.5%的小剂量高压布比卡因辅助使用时,可以更早地行走,且无并发症。
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