A Promising New Therapeutic Modality in the Treatment of Recurrent Vulvovaginitis: Ozone therapy

IF 0.8 Q4 REPRODUCTIVE BIOLOGY
S. Ulger
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引用次数: 0

Abstract

diagnosed in the primary health care. It affects 75% of the women once in their life and 40% of them face with recurrent episodes. The term of recurrent vulvo-vaginitis is considered when the disease repeats four or more times per year. The disease is not easily resolved due to the traditional self-treatment modalities and the most important reason is the extensive abuse of antibiotics, fungicides, and vaginal antiseptics. These factors complicate the disease, rises the antibiotic resistance, and worsen the wonderful complex microecological system of the vagina (1). In healthy women, the vaginal microbiota is dominated by H2O2-producing Lactobacillus which maintains the normal acidic environment of the vagina (2). Any change in this microecological system will cause a variety of vaginal infections. The general conventional treatment with antibiotics also destroys this beneficial bacterial flora leading to a more chronic and complex disease. It is necessary to search new treatment modalities that will effectively solve the problem while protecting the balance and function of the vaginal microecological system (3). Ozone is a trioxygen (O3), highly reactive inorganic gaseous molecule which is known as the third strongest oxidant molecule in the world. Ozone is a natural part of the atmosphere produced by ultraviolet light and a high-pressure diatomic oxygen in the stratosphere layer. It was discovered in the mid-nineteenth century, however its usage as a medical drug is in recent decades (4). It is known as a strong disinfectant with perfect antibacterial, antiviral, antifungal, and anti-parasitic properties. With a stronger oxidant effect, ozone is an important microorganism killer while protecting beneficial microorganisms and healthy tissue (5). It has been shown that the dominance of lactobacillus come back, and normal vaginal environment is rebuilt after vaginal ozone treatment in the vulvovaginitis patients (3). Bocci, a physiologist, has studied ozone for long years and identified this new medical drug as a wonder drug of 21st century (5). Ozone has a key role in the human A Promising New Therapeutic Modality in the Treatment of Recurrent Vulvovaginitis: Ozone therapy
一种治疗复发性外阴阴道炎的新方法:臭氧疗法
在初级卫生保健中诊断。75%的女性一生中会患一次,其中40%的女性会反复发作。复发性外阴阴道炎被认为是疾病每年重复四次或四次以上。由于传统的自我治疗方式,该病不易解决,最重要的原因是抗生素、杀菌剂和阴道防腐剂的广泛滥用。这些因素使疾病复杂化,增加了抗生素耐药性,并使阴道奇妙复杂的微生态系统恶化(1)。在健康女性中,阴道微生物群以产生h2o2的乳酸杆菌为主,乳酸杆菌维持阴道正常的酸性环境(2)。这种微生态系统的任何变化都会引起各种阴道感染。一般的常规抗生素治疗也会破坏这种有益的菌群,导致更慢性和复杂的疾病。有必要寻找新的治疗方法,既能有效解决问题,又能保护阴道微生态系统的平衡和功能(3)。臭氧是一种三氧(O3),是一种高活性的无机气体分子,被称为世界上第三强的氧化剂分子。臭氧是大气的自然组成部分,由紫外线和平流层中的高压双原子氧产生。它是在19世纪中期被发现的,然而它作为一种药物的使用是在最近几十年(4)。它被认为是一种强消毒剂,具有完美的抗菌、抗病毒、抗真菌和抗寄生虫的特性。臭氧具有较强的氧化作用,在保护有益微生物和健康组织的同时,也是重要的微生物杀手(5)。研究表明,外阴阴道炎患者经阴道臭氧治疗后,乳酸菌的优势恢复,正常阴道环境重建(3)。对臭氧进行了多年的研究,并将这种新型药物确定为21世纪的神奇药物(5)。臭氧在人类复发性外阴阴道炎的治疗中起着关键作用
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来源期刊
CiteScore
1.60
自引率
14.30%
发文量
8
期刊介绍: All kind of knowledge contributing to the development of science by its content, value, level and originality will be covered by IJWHR. Problems of public health and their solutions are at the head of the windows opening us to the world. The "International Journal of Women''s Health and Reproduction Sciences” is a modern forum for scientific communication, covering all aspects women health and reproduction sciences, in basic and clinical sciences, mainly including: -Medical Education in Women Health and Reproduction Sciences -Cardiology in Women Health-Related Reproductive Problems -Sports Medicine in Women Health and Reproduction Sciences -Psychiatry in Women Health-Related Reproductive Problems -Antioxidant Therapy in Reproduction Medicine Sciences -Nutrition in Women Health and Reproduction Sciences -Defense Androgen and Estrogen -Fertility and Infertility -Urogynecology -Endometriosis -Endocrinology -Breast Cancer -Menopause -Puberty -Eroticism -Pregnancy -Preterm Birth -Vaginal Diseases -Sex-Based Biology -Surgical Procedures -Nursing in Pregnancy -Obstetrics/Gynecology -Polycystic Ovary Syndrome -Hyperandrogenism in Females -Menstrual Syndrome and Complications -Oncology of Female Reproductive Organs -Traditional Medicine in Women Reproductive Health -Ultrasound in Women Health Reproduction sciences -Stem Cell Research In Women Reproduction Sciences -Complementary Medicine in Women Reproductive Health -Female Sexual Dysfunction: Pathophysiology & Treatment
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