Relationship Between Placental Calcification and Estimated Fetal Weight Percentile at 30-34 Weeks of Pregnancy

IF 0.8 Q4 REPRODUCTIVE BIOLOGY
M. Barati, S. Masihi, Elnaz Barahimi, M. Khorrami
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引用次数: 1

Abstract

Objectives: The identification of at-risk fetus is considered as one of the most difficult challenges for clinicians and researchers although the clinical significance of placental calcifications (PCs) and its relation to adverse pregnancy outcome are controversial. Therefore, the present study aimed to evaluate the relationship between PC and estimated fetal weight (EFW) percentile at 30-34 weeks of pregnancy. Materials and Methods: This prospective cross-sectional study was carried out on all pregnant women except for multiple pregnancy subjects who were admitted to an outpatient perinatal center from October 2016 to September 2018. Several parameters were measured at 30-34 weeks of pregnancy, including EFW, umbilical artery pulsatility index (PI), middle cerebral artery PI, cerebroplacental ratio (CPR), right and left uterine artery PI, along with right and left uterine artery notch. Finally, the calcification of the placenta with any shape and degree was determined as well. Results: In this study, 739 pregnant women were evaluated for PC, including patients with PC (9.87%), small-for-gestational age (SGA, 3.65%), and those with at least one abnormal Doppler index (23.95%). Patients with PC and those with at least one abnormal Doppler index had significantly higher SGA (29.62% and 12.42%, respectively). In addition, there were 55.55% and 30.13% patients with SGA and PC in the group with at least one abnormality in terms of Doppler indices. Conclusions: In general, the findings showed that PC is more common in SGA. Based on the results, at least one abnormality in Doppler indices was more common in PC and SGA, and uterine artery Doppler abnormality was the most prevalent abnormal findings in the arterial Doppler. Thus, PC may be an important marker for adverse pregnancy outcomes.
胎盘钙化与妊娠30-34周胎儿体重百分位数的关系
目的:尽管胎盘钙化(PCs)的临床意义及其与不良妊娠结局的关系存在争议,但高危胎儿的识别被认为是临床医生和研究人员面临的最困难的挑战之一。因此,本研究旨在评估PC与妊娠30-34周估计胎儿体重(EFW)百分位数之间的关系。材料与方法:本前瞻性横断面研究对2016年10月至2018年9月在门诊围产中心就诊的除多胎妊娠外的所有孕妇进行研究。于妊娠30 ~ 34周测定EFW、脐动脉搏动指数(PI)、大脑中动脉PI、脑胎盘比(CPR)、左右子宫动脉PI及左右子宫动脉切迹。最后,确定胎盘的任何形状和程度的钙化。结果:本研究共对739例孕妇进行了PC检查,包括PC(9.87%)、小胎龄(3.65%)和至少一项多普勒指数异常(23.95%)。PC及至少有一项多普勒指数异常的患者SGA显著增高(分别为29.62%和12.42%)。此外,多普勒指数至少有一项异常的SGA和PC患者分别占55.55%和30.13%。结论:总的来说,研究结果显示PC在SGA中更为常见。结果显示,PC和SGA多见至少一项多普勒指标异常,其中子宫动脉多普勒异常是动脉多普勒最常见的异常表现。因此,PC可能是不良妊娠结局的重要标志。
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来源期刊
CiteScore
1.60
自引率
14.30%
发文量
8
期刊介绍: All kind of knowledge contributing to the development of science by its content, value, level and originality will be covered by IJWHR. Problems of public health and their solutions are at the head of the windows opening us to the world. The "International Journal of Women''s Health and Reproduction Sciences” is a modern forum for scientific communication, covering all aspects women health and reproduction sciences, in basic and clinical sciences, mainly including: -Medical Education in Women Health and Reproduction Sciences -Cardiology in Women Health-Related Reproductive Problems -Sports Medicine in Women Health and Reproduction Sciences -Psychiatry in Women Health-Related Reproductive Problems -Antioxidant Therapy in Reproduction Medicine Sciences -Nutrition in Women Health and Reproduction Sciences -Defense Androgen and Estrogen -Fertility and Infertility -Urogynecology -Endometriosis -Endocrinology -Breast Cancer -Menopause -Puberty -Eroticism -Pregnancy -Preterm Birth -Vaginal Diseases -Sex-Based Biology -Surgical Procedures -Nursing in Pregnancy -Obstetrics/Gynecology -Polycystic Ovary Syndrome -Hyperandrogenism in Females -Menstrual Syndrome and Complications -Oncology of Female Reproductive Organs -Traditional Medicine in Women Reproductive Health -Ultrasound in Women Health Reproduction sciences -Stem Cell Research In Women Reproduction Sciences -Complementary Medicine in Women Reproductive Health -Female Sexual Dysfunction: Pathophysiology & Treatment
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