A Short-Term Clinical Analysis of Q-Value-Guided Micro-Monovision LASIK for Myopic Astigmatism and Presbyopia

L. Hui, W. Qing, Ma Yuna, Liang Jiangfeng
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Abstract

Objective: To evaluate the safety, effectiveness and predictability of Q-value-guided micro-monovision laser in situ keratomileusis (LASIK) in the treatment of myopia and presbyopia. Methods: A prospective study was performed based on 35 patients (70 eyes) with myopia and presbyopia, who underwent Q-value-guided micro-monovision LASIK in the Affiliated Hospital of Qingdao University from August 2017 to May 2018. At the 3-month postoperative visit, examinations were performed that included binocular and monocular distance and near visual acuity (logMAR), manifest refraction, contrast sensitivity (CS) and stereopsis. In addition, questionnaires of asthenopic symptoms due to near-distance work were also included for all the patients 3 months postoperatively. The data before and after surgery were analyzed using a paired t test. Results: Binocular distance best-corrected visual acuity (BCVA) was 0.01±0.06 before surgery and was -0.04±0.21 at 3 months after surgery. Thus, none of the eyes lost one line after the operation. Uncorrected visual acuity (UCVA) of the dominant eye and the non-dominant eye were -0.04±0.19 and 0.04±0.13, respectively. In all patients, near distance UCVA of the dominant eye was equal to 20/25 or above, and that of the non-dominant eye was 20/20. In addition, the difference between the actually obtained spherical equivalent (SE) and target SE was in the range of ±0.50 D and ±1.00 D for 60 eyes (86%) and 75 eyes (100%), respectively. At 3 months after surgery, CS had a significant improvement of 18.0 c/d spatial frequency under day+peripheral glare (t=-2.504, P=0.017). The spatial frequencies for day 1.5 c/d, 6.0 c/d and 18.0 c/d, day+peripheral glare 6 c/d, night 1.5 c/d and night+peripheral glare 18.0 c/d had significantly decreased compared to that before surgery (P<0.05). All other conditions were restored to preoperative levels. There was no significant difference in stereopsis before and after surgery. No patients suffered from headache, nausea, blurred reading or difficulty with nearsightedness after near-distance work at 3 months postoperatively. All patients (100%) were satisfied with the results of the operation. Conclusions: The Q-value-guided micro-monovision LASIK protocol is a safe, effective and predictable method for the treatment of myopic patients with presbyopia. Patients can obtain better binocular distance, near vision and visual function simultaneously. Key words: myopia; Q value; presbyopia laser in situ keratomileusis; contrast sensitivity; stereopsis
q值引导微单视LASIK治疗近视散光和老花眼的短期临床分析
目的:评价q值引导微单视激光原位角膜磨除术(LASIK)治疗近视和老花眼的安全性、有效性和可预测性。方法:对2017年8月至2018年5月青岛大学附属医院行q值引导微单视LASIK手术的35例(70眼)近视老花患者进行前瞻性研究。术后3个月随访,检查包括双眼和单眼距离和近视敏度(logMAR)、明显屈光、对比敏感度(CS)和立体视觉。此外,对所有患者术后3个月进行近距离工作引起的衰弱症状问卷调查。手术前后数据采用配对t检验进行分析。结果:双眼最佳矫正视力(BCVA)术前为0.01±0.06,术后3个月为-0.04±0.21。因此,手术后没有一只眼睛失去一条线。优势眼和非优势眼未矫正视力(UCVA)分别为-0.04±0.19和0.04±0.13。所有患者优势眼近距离UCVA≥20/25,非优势眼近距离UCVA≥20/20。另外,60只眼(86%)和75只眼(100%)实际获得的球面等效(SE)与目标SE的差值分别在±0.50 D和±1.00 D范围内。术后3个月,CS在白天+周边眩光下的空间频率显著提高18.0 c/d (t=-2.504, P=0.017)。与术前相比,白天1.5 c/d、6.0 c/d、18.0 c/d、白天+周边眩光6 c/d、夜间1.5 c/d、夜间+周边眩光18.0 c/d的空间频率显著降低(P<0.05)。其他情况均恢复到术前水平。手术前后立体视功能差异无统计学意义。术后3个月无患者出现头痛、恶心、阅读模糊、近视眼困难等症状。所有患者(100%)对手术效果满意。结论:q值引导下的微单视LASIK治疗近视合并老花眼是一种安全、有效、可预测的方法。患者可同时获得较好的双眼距离、近视力和视觉功能。关键词:近视;Q值;老花激光原位角膜磨镶术;对比敏感度;立体观测
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