Medicazione a base d’argento nella gestione dell’emergenza cutanea

Walter Lunardi, S. Bianchi
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Abstract

Introduction: Exit-site (ES) and tunnel infections are the main infectious complication in peritoneal dialysis (PD); they also are risk factors for the development of peritonitis, for catheter removal and for dialysis drop-out. Up to now, besides the recommendations of the Guidelines there is no uniformity, nor on the classification, nor on the treatment strategies of the infected ES. Recent experiences are reported with alternative types of dressings that aim to reduce the incidence of ES infection and consequently of the subcutaneous tunnel. Methods: The Tuscan group conducted a retrospective observational study of 10 patients on PD who, showing signs of a suspected but not ascertained infection (negative microbiological culture), such as redness, edema, secretion, scab, had been medicated with silver-ions releasing Exit-Pad Ag. The aim was to evaluate and classify the evolution of ES lesions, in order to confirm the preventive efficacy of the silver-ions releasing dressing compared to the traditional ones. Results: After 4 weeks of treatment with Exit Pad Ag maintained in situ for 72 h, 6 patients no longer had any signs of inflammation. In 2 cases, several weeks of treatment were necessary to achieve a complete recovery, while in 2 other cases the signs of inflammation became negative in less time (2 weeks, 1 week). Conclusions: With the utilization of an alternative dressing such as Exit-Pad Ag on PD patients showing early signs of inflammation, the onset of a true infection can be prevented, with a progressive improvement of the ES.
皮肤紧急情况下的银色敷料
腹膜透析(PD)的主要感染并发症为出口部位(ES)和隧道感染;它们也是发展为腹膜炎,导管移除和透析退出的危险因素。到目前为止,除了指南的建议外,对感染ES的分类和治疗策略也没有统一。最近的经验报告了替代类型的敷料,旨在减少ES感染的发生率,从而减少皮下隧道。方法:托斯卡纳组对10例PD患者进行回顾性观察研究,这些患者表现出疑似感染但未确定感染的迹象(微生物培养阴性),如红肿、水肿、分泌物、结痂,并给予银离子释放的export - pad Ag。目的是评估和分类ES病变的演变,以确认银离子释放敷料与传统敷料相比的预防效果。结果:Exit Pad Ag原位放置72 h,治疗4周后,6例患者不再出现任何炎症迹象。其中2例需要数周的治疗才能完全恢复,而另外2例炎症症状在更短的时间内变为阴性(2周,1周)。结论:对出现早期炎症症状的PD患者使用替代敷料,如Exit-Pad Ag,可以预防真正感染的发生,并逐步改善ES。
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