Palladium-catalyzed transfer hydrogenation of terminal alkynes using ethanol as the hydrogen donor

Journal of Chemical Research-s Pub Date : 2022-11-01 DOI:10.1177/17475198221145838

Jie Hui, Feng Wang

引用次数: 0

Abstract

A ligand-promoted, palladium-catalyzed transfer hydrogenation of terminal alkynes using ethanol as the hydrogen donor is developed. The chemical selectivity control is achieved based on ligand regulation. The use of triethanolamine and tetrahydrofuran at 80 °C under N2 is found to be critical for the transfer hydrogenation of terminal alkynes. The general applicability of this procedure is highlighted by the synthesis of 27 terminal alkenes in moderate to good yields.

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钯催化乙醇为氢供体的末端炔转移加氢反应

研究了以乙醇为氢供体，配体促进的钯催化末端炔的转移加氢反应。通过配体调控实现化学选择性控制。三乙醇胺和四氢呋喃在80℃N2下的使用对末端炔的转移加氢至关重要。该方法的普遍适用性是突出的27个终端烯烃的合成在中等至良好的产量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Chemical Research-s 化学科学, 有机化学, 有机合成

自引率

0.00%

发文量

审稿时长

1 months

期刊介绍： The Journal of Chemical Research is a peer reviewed journal that publishes full-length review and research papers in all branches of experimental chemistry. The journal fills a niche by also publishing short papers, a format which favours particular types of work, e.g. the scope of new reagents or methodology, and the elucidation of the structure of novel compounds. Though welcome, short papers should not result in fragmentation of publication, they should describe a completed piece of work. The Journal is not intended as a vehicle for preliminary publications. The work must meet all the normal criteria for acceptance as regards scientific standards. Papers that contain extensive biological results or material relating to other areas of science may be diverted to more appropriate specialist journals. Areas of coverage include: Organic Chemistry; Inorganic Chemistry; Materials Chemistry; Crystallography; Computational Chemistry.