Effects of intradialytic exercise on functional capacity in patients with end-stage chronic kidney disease: a systematic review and meta-analysis.

IF 2.4 4区医学 Q3 NEUROSCIENCES

BMC Neuroscience Pub Date : 2024-01-01 Epub Date: 2022-05-27 DOI:10.1080/15438627.2022.2079983

Aline M Araujo, Rafael B Orcy, Natan Feter, Marina K Weymar, Rodrigo K Cardoso, Maristela Bohlke, Airton J Rombaldi

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引用次数: 2

Abstract

The study aimed to investigate the effect of intradialytic exercise training programmes on the submaximal functional capacity of patients with kidney failure. We searched for randomized clinical trials that assessed submaximal functional capacity using the 6-min walk test (6 MWT) in adult patients on maintenance haemodialysis submitted to intradialytic physical training. The search was performed on 15 October 2021, in different databases. Random-effect, multivariate meta-regression adjusted for multiplicity were performed to examine the relationship between exercise effect and covariates. Intradialytic physical exercise induced greater changes in 6MWT distance (k = 18; n = 1,458; WMD: 37.0; 95% CI 29.3; 50.6 metres) than control groups, with substantial heterogeneity (I2 = 78.3%). Aerobic, strength, and combined exercise promoted an average increase of 48.7 (95%CI 30.9; 66.4 metres), 16.9 (95%CI 7.6; 26.3 metres), and 75.8 (95%CI 55.1; 96.6 metres) metres, respectively. Strength training resulted in inferior gains in 6MWT distance compared to aerobic training (WMD: -25.0; 95%CI: -49.1; -0.9). Intervention length shorter than 11 weeks (WMD: 37.0; 95%CI: -5.4; 79.3 metres) did not induce greater changes in 6MWT compared to control groups. There was a positive response in submaximal functional capacity to intradialytic training in kidney failure patients on maintenance haemodialysis.

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肾内锻炼对终末期慢性肾病患者功能能力的影响：系统回顾和荟萃分析。

本研究旨在探讨肾内透析运动训练计划对肾衰竭患者亚极限功能能力的影响。我们搜索了使用 6 分钟步行测试（6 MWT）评估接受血液透析内体育训练的维持性血液透析成年患者亚极限功能能力的随机临床试验。搜索于 2021 年 10 月 15 日在不同的数据库中进行。对多重性进行调整的随机效应多变量元回归研究了锻炼效果与协变量之间的关系。与对照组相比，椎管内体育锻炼引起的6MWT距离变化更大（k = 18；n = 1,458；WMD：37.0；95% CI 29.3；50.6米），但存在很大的异质性（I2 = 78.3%）。有氧运动、力量运动和综合运动分别促进了 48.7 米（95%CI 30.9 米；66.4 米）、16.9 米（95%CI 7.6 米；26.3 米）和 75.8 米（95%CI 55.1 米；96.6 米）的平均增长。与有氧训练相比，力量训练在 6MWT 距离上的收益较低（WMD：-25.0；95%CI：-49.1；-0.9）。与对照组相比，干预时间短于11周（WMD：37.0；95%CI：-5.4；79.3米）的6MWT没有引起更大的变化。接受维持性血液透析的肾衰竭患者对肾内透析训练的亚极限功能能力有积极的反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMC Neuroscience 医学-神经科学

CiteScore

3.90

自引率

0.00%

发文量

审稿时长

16 months

期刊介绍： BMC Neuroscience is an open access, peer-reviewed journal that considers articles on all aspects of neuroscience, welcoming studies that provide insight into the molecular, cellular, developmental, genetic and genomic, systems, network, cognitive and behavioral aspects of nervous system function in both health and disease. Both experimental and theoretical studies are within scope, as are studies that describe methodological approaches to monitoring or manipulating nervous system function.