Haematological Indices of HIV Seropositive Subjects at Nnamdi Azikiwe University Teaching Hospital (Nauth), Nnewi

Abstract

This study was carried out to provide information on the haematologic indices of HIV Patients on ART and those not on ART. Blood sample was collected from 160 subjects, 55 HIV-infected patients on antiretroviral therapy (ART), 55 HIV-infected patients not on ART and 50 apparently healthy HIV Sero-negative individuals as controls. Platelet (PLT), Total white blood cell Count (TWBC), Lymphocyte Count (LYMPH), Neutrophil Count (NEUT), Haemoglobin (HGB), Red Blood Cell Count (RBC), Mean Cell Volume (MCV), Mean cell Haemoglobin (MCH), Mean Cell Haemoglobin Concentration (MCHC), Red Cell Distribution Width (RDW), Platelet Distribution Width (PDW), Mean Platelet Volume (MPV) and Retroviral screening (RVS) of the subjects were determined using standard methods after obtaining ethics approval and informed consent of the subjects. ANOVA and t-test were used for statistical analysis. HGB, RBC and MCHC were significantly lower in HIV patients (F=60.57; 19.26; 12.83; 9.84; P<0.05 respectively) compared with control subjects. HCT, HGB, MCV, MCH and RDW of HIV patients on ART were significantly higher (t=2.96; 3.04; 6.30; 5.10; P<0.05 respectively) compared with HIV patients not on ART.