Y-STR Haplotypic Polymorphisms for the Hakka Population in West China and Phylogenic Comparison with Other Chinese Populations

4区生物学 Q2 Medicine

Human Biology Pub Date : 2022-09-23 DOI:10.1353/hub.2017.0109

Mengnan Liu, Chang-Xiu Peng, Dan-Lu Song, H. Jin, Xingjuan Zheng, Guangyao Fan

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引用次数: 0

Abstract

The Hakka, who have undergone a series of great migrations, are usually identified with people who speak the Hakka language or share at least same Hakka ancestry. As the largest Hakka dialect island in West China, the Dongshan region was closely linked with the great migration wave of Hakka. However, the paternal genetic profiles of Dongshan Hakka have never been revealed. In the present study, 41 Y-chromosomal short tandem repeat (Y-STR) loci included in the SureID PathFinder Plus Kit were analyzed in 353 unrelated male individuals (171 Hakka and 182 Han) of Sichuan Province, China. By analyzing 166 different haplotypes among Dongshan Hakka and 176 different haplotypes among Sichuan Han males, haplotype diversity was calculated as 0.9997, with a discrimination capacity of 0.9708, for the Hakka population, and 0.9996 and 0.9670 for the Sichuan Han population, respectively. Most of the Y-STR loci were highly informative in both populations except DYS645. The genetic relationships were evaluated by comparing the Hakka population with 11 other groups that are relevant to Hakka migration routes. The results of the multidimensional scaling plot and phylogenetic tree indicate that the Dongshan Hakka population was closely related to Han nationalities from Anhui, Jiangxi, and Fujian Provinces.

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中国西部客家人群Y-STR单倍型多态性及其与中国其他人群的系统发育比较

客家人经历了一系列的大迁徙，通常被认为是说客家话或至少有相同客家血统的人。作为中国西部最大的客家方言岛，东山地区与客家大迁徙浪潮密切相关。然而，东山客家父系遗传图谱一直未被揭示。本研究利用SureID PathFinder Plus试剂盒中包含的41个y染色体短串联重复(Y-STR)位点，对353名无亲缘关系的四川男性个体(171名客家人和182名汉族)进行了分析。通过分析东山客家群体的166种不同单倍型和四川汉族群体的176种不同单倍型，计算出客家群体的单倍型多样性为0.9997，辨别能力为0.9708，四川汉族群体的单倍型多样性为0.9996，辨别能力为0.9670。除DYS645外，其余Y-STR基因座在两种人群中均具有较高的信息性。通过与其他11个与客家人迁徙路线相关的群体进行比较，评估了客家人群体的遗传关系。多维标度图和系统发育树分析结果表明，东山客家人与安徽、江西、福建等地的汉族有着密切的亲缘关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Human Biology 生物-生物学

CiteScore

1.90

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Human Biology publishes original scientific articles, brief communications, letters to the editor, and review articles on the general topic of biological anthropology. Our main focus is understanding human biological variation and human evolution through a broad range of approaches. We encourage investigators to submit any study on human biological diversity presented from an evolutionary or adaptive perspective. Priority will be given to interdisciplinary studies that seek to better explain the interaction between cultural processes and biological processes in our evolution. Methodological papers are also encouraged. Any computational approach intended to summarize cultural variation is encouraged. Studies that are essentially descriptive or concern only a limited geographic area are acceptable only when they have a wider relevance to understanding human biological variation. Manuscripts may cover any of the following disciplines, once the anthropological focus is apparent: human population genetics, evolutionary and genetic demography, quantitative genetics, evolutionary biology, ancient DNA studies, biological diversity interpreted in terms of adaptation (biometry, physical anthropology), and interdisciplinary research linking biological and cultural diversity (inferred from linguistic variability, ethnological diversity, archaeological evidence, etc.).