Mismatch negativity in auditory neuropathy/auditory dys-synchrony

T. Gabr
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引用次数: 4

Abstract

Abstract Auditory neuropathy/auditory dys-synchrony (AN/AD) is a recently described hearing disorder that has unique pathologies and perceptual consequences. Difficulty in understanding speech is a consistently reported consequence of this type of hearing loss. These patients can detect speech sounds but cannot discriminate what they have heard. Objectives: This work was designed to investigate fine discrimination abilities in these patients and to assess the possibility of there being any abnormalities which might contribute to the difficulty in speech perception. Method: Subjects were classified into 2 groups: control group (GI) composed of 20 normal hearing subjects and the study group (GII) composed of 17 AN/AD patients. All cases were subjected to: full audiological history, otological examination, basic audiological evaluation, Mismatch Negativity (MMN) using tone stimuli in 4 paradigms. Results: MMN response was significantly delayed in AN/AD group when compared to control with some difference between tested frequencies. Conclusion: MMN provided an excellent tool for assessing fine discrimination in AN/AD patients.
听神经病变/听觉不同步中的错配负性
听觉神经病变/听觉不同步(AN/AD)是一种最近被描述的听力障碍,具有独特的病理和感知后果。这种类型的听力损失经常导致理解语言的困难。这些病人能察觉到说话的声音,但不能区分他们听到的是什么。目的:本研究旨在探讨这些患者的精细辨别能力,并评估可能导致言语感知困难的任何异常的可能性。方法:将受试者分为两组:对照组(GI) 20例听力正常者和研究组(GII) 17例AN/AD患者。所有病例均接受完整听力学史、耳科检查、基础听力学评估、4种模式下的音调刺激失配负性(MMN)测试。结果:与对照组相比,AN/AD组MMN反应明显延迟,且测试频率之间存在一定差异。结论:MMN是评估an /AD患者精细鉴别的良好工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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