Changes in the Cancer Antigen Markers in the Pleural Liquid During Chemotherapy among Ovarian Cancer Patients

Abbas Abdulmueed Mustafa Alani, Ihab Q. Ali, Yasir Khaleel Almusawi
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Abstract

The silent killer or ovarian cancer (OC) is one of the major causes of cancer deaths among women in themodern age. In view of the therapeutic roles of platinum based chemotherapy among the ovarian cancerpatients, objective of this report was to assess the effects of the first round of chemotherapy among womenwith ovarian cancer. Here, the levels of the pleural markers for cancer bio markers, before and after thechemotherapy were tested among ovarian cancer patients. The biochemical indices may be of use indeciphering the relation between cancer relapse and platinum retrieval. The pleural analyses pre and postplatinum chemotherapy session demonstrated wide range of biochemical and protein marker changes amongovarian cancer patients. The various cancer antigens were variedly reduced post chemotherapy. Hence, it isproposed that biochemical markers in pleural liquid may serve as better indicators and early diagnostic toolsfor ovarian cancer.
卵巢癌患者化疗期间胸膜液肿瘤抗原标记物的变化
无声杀手卵巢癌(OC)是现代女性癌症死亡的主要原因之一。鉴于铂类化疗在卵巢癌患者中的治疗作用,本报告的目的是评估第一轮化疗在卵巢癌女性患者中的效果。这里,卵巢癌患者化疗前后胸膜癌症生物标志物的水平进行了测试。这些生化指标可能有助于解释癌症复发与铂恢复的关系。铂类化疗前后的胸膜分析表明,卵巢肿瘤患者的生化和蛋白质标志物发生了广泛的变化。化疗后,各种癌症抗原都有不同程度的减少。因此,我们认为胸膜液中的生化指标可作为卵巢癌较好的指标和早期诊断工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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