An Efficient, Green synthesis of Ethyl/Methyl 4-(3-Aryl-1- Phenl-1H-Pyrazol-4-yl)-6-Methyl-2-oxo-1,2,3,4- Tetrahydropyrimidine-5-Carboxylates

Abstract

An efficient, green heterogeneous catalyst was developed for one-pot three component synthesis of Ethyl/methyl 4-(3-aryl-1-phenyl-1H-pyrazol-4-yl)-6-methyl-2-oxo1,2,3,4-tetrahydropyrimidine-5-carboxylate derivatives by the condensation of aldehydes, acetoacetate, and urea in the presence of 5% WO3/ZrO2 heterogenous catalyst under solventfree condition