Comparison of MELASQOL and DLQI in female patients suffering from melasma and nonmelasma facial melanosis: a cross-sectional study

Abstract

Background: Facial melanosis is a common clinical problem and results in impaired quality of life. Aims: The aim of the study was to compare the quality of life in female patients suffering from melasma and nonmelasma facial melanosis (NMFM) using melasma quality of life (MELASQOL) and dermatology life quality index (DLQI). Methods: It was a prospective cross-sectional study conducted in a dermatology outpatient department of tertiary care center. Modified melasma area severity index (mMASI), MELASQOL, and DLQI were calculated in female patients meeting inclusion criteria of the study. The statistical analysis was performed using statistical package for social sciences (SPSS version 20; Chicago, IL, USA). Categorical data are presented as number with percentage and continuous data as mean with standard deviation. Quantitative data were compared using independent t test and categorical data using Chi-square test. All statistical tests were two sided and were performed at a significance level of α = 0.05. Results: A total of 119 patients were included in the study and consisting of 50 (42%) patients with melasma and 69 (58%) patients with NMFM. The impairment of quality of life was more in NMFM when compared with melasma group. The severity of pigmentation (mMASI) did not show any significant correlation with MELASQOL or DLQI in either of the groups. There was strong correlation between DLQI and MELASQL (Spearman rho = 0.886; P < 0.001). Conclusion: Facial melanosis impacts quality of life adversely. The impact of NMFM is more when compared with melasma. MELASQOL and DLQI should be performed in these patients to understand true impact of these diseases on quality of life.