介孔分子筛MCM-41固载磷钨酸催化苯并三氮唑与查尔酮的氮杂迈克加成反应研究 Aza-Michael Addition of Chalcone with Benzotriazole Catalyzed by MCM-41 Immobilized H3PW12O40

Abstract

以介孔分子筛MCM-41固载磷钨酸为催化剂，对苯并三氮唑与查尔酮进行了氮杂迈克加成的催化研究。经过条件筛选，发现MCM-41中的磷钨酸负载量对该反应体系有很大的影响，其中50 wt%的磷钨酸负载量更有利于反应的进行，产率可达98%。通过NMR对产物结构进行了表征，并且催化剂具有一定的回收再利用效果。 In this paper, mesoporous siliceous material MCM-41 supported H3PW12O40 (PW) could act as an efficient catalyst for the aza-Michael addition reaction of chalcone with benzotriazole. As can be seen from a serial of reaction conditions, the ratio of PW and MCM-41 plays a critical role in the reaction, and the best catalyzed result was achieved when using 50 wt% PW/MCM-41, and the yield was up to 98%. All the products were confirmed by NMR techniques. Moreover, the catalyst was also found to exhibit better recyclability.