Liquid Chromatographic Methods for Anti-tubercular Agents: An Overview

Abstract

The aim of this review is to summarise the different analytical and bioanalytical methods used to determine the concentration of anti-tubercular agents from last few years. As we know that tuberculosis is a life threatening disease and second to HIV in terms of deaths due to infectious diseases. Drug resistance development of the first-line drugs is a most important concern in the cure of this disease. There is no comprehensive and critical review in the literature for the analytical and bioanalytical methods for the determination of ant-tubercular agents from last few years. So this work provides the detailed account on the chromatographic methods reported in the literature for the estimation of various ant-tubercular drugs.