Villoglandulary papillary adenocarcinoma co-existing with high-grade squamous intraepitelial lesion; arising from an endocervical polyp

Abstract

Adenocarcinomas account for 10–20% of invasive cervical carcinomas. The villoglandular papillary adenocarcinoma has been recognized as a subtype of mucinous adenocarcinoma and identified as a distinctive histological entity from the usual invasive adenocarcinomas of the uterine cervix. We report a new case of villoglandulary papillary adenocarcinoma, which was peculiar because of its association with a co-existing high grade squamous intraepithelial lesion and arising from an endocervical polyp. Excellent prognosis of isolated villoglandulary papillary adenocarcinoma is important in terms of making differential diagnosis from other adenocarcinomas and eliminating unnecessary aggressive treatments. It is also important to keep in mind for pathologists since it allows them to examine endocervical polyps that we often encounter in daily life and shows that malignant tumoral lesions can develop from polyps.