Imaging of D-cell: Aromatic L-amino acid decarboxylase (AADC)-immunoreactive glial cell found in Parkinsonian striatum

Abstract

Aromatic L-amino acid decarboxylase (AADC = DDC, dopa decarboxylase)-immunoreactive glial cells, so-called D-cells, were seen in the striatum of a case with Parkinson’ s disease who had been prescribed L-dopa, surrounding perivascular spaces. The vascular walls of Parkinsonian striatum as well as cases without neuropsychiatric diseases contained AADC. The mechanism of AADC-immunoreactive glial cell expression is yet unclear.