COVID-19 mRNA vaccine-induced lung injury: A case report

Abstract

Abstract Vaccination is the most effective method for preventing severe COVID-19 illness. With billions of people having received the COVID-19 mRNA vaccine, rare adverse events are now surfacing. We report a case of acute lung injury with concurrent inflammatory pneumonitis, pneumothorax and pulmonary emboli following mixed COVID-19 mRNA vaccination. The patient was admitted to hospital for hypoxemic respiratory failure and gradually improved clinically and radiographically after treatment with steroids. As our population is vaccinated against COVID-19, including boosters, mixed vaccination will undoubtably become more common. It will therefore be important to recognize that lung injury may be a rare but serious adverse reaction to the COVID-19 mRNA vaccine, with mixed mRNA vaccination being a possible added risk factor.