Antiseptic Treatment of Povidone-Iodine Solution as a Countermeasure against Staphylococcus Aureus in Atopic Dermatitis

Abstract

Many patients with atopic dermatitis have not only skin but also multiple organ disorders such as intestinal tract and cervical spine. As the cause, the involvement of a toxin (called superantigen) produced by Staphylococcus aureus, which is detected from the skin of atopic dermatitis, is presumed. As a measure against Staphylococcus aureus, the use of Povidone-iodine was listed as adjuvant therapy in the Japanese Guidelines for Atopic Dermatitis Treatment 2018. In the future, we would like to treat atopic dermatitis as a superantigen disease and propose that Povidone-iodine solution be used in combination with general treatment as a measure against Staphylococcus aureus.