Experimental study on aerosol inhalation of the human upper airway

Abstract

The study of aerosol deposition in the human upper respiratory tract is of great significance for understanding the impact of toxic aerosols on human health and improving the therapeutic effect of drug aerosol inhalation. 3D printing technology was used in the experimental model of the human upper airway. A laser particle size analyzer was used to study the deposition of aerosol particles with a particle size of 1-20 μm inhaled in the upper respiratory tract of the human body, and the particle deposition rules of the aerosol particles in the upper respiratory tract were analyzed. The experimental results show that aerosol particles remain more in the pharynx, larynx and position. For particles with a particle size of 1-5 μm, more deposition will occur in the trachea, and for particles with a particle size of 10-20 μm, most of them will be deposited in the mouth.