Evaluation of Phytochemical, Total phenolic and Antioxidant Activity of Carica Papaya Seed for Its Use in Biosynthesis of Gold Nanoparticles

The Egyptian Journal of Chemistry Pub Date : 2021-04-19 DOI:10.21608/EJCHEM.2021.63985.3371

S. A. Farhan, R. M. Dadoosh, A. M. Jassim

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引用次数: 5

Abstract

Synthesis of nanoparticles using green methods with study of their propertie is one of great researchers’ concerns in fields of pharmaceutical and biomedical products. The present paper aiming to use of an eco-friendly route is used for biosynthesis of gold nanoparticles (AuNPs) using C. Papaya seeds as both reducing and stabilizing agent. Study of C. Papaya seed contents showed many compounds which analyzed via qualitative, quantitative and GC-MS analysis. The influence of C. Papaya concentration, contact time and temperature on the reaction rate and shape of AuNPs are confirmed The biosynthesized NPs are characterize via UV-Vis, AFM and SEM. The AFM and SEM analysis exhibit a size between 40-105nm with average diameter 75.68nm, and spherical in structure. The antioxidant activity and free radical scavenge activity are studied by using TLC and DPPH analysis. The results show that the C. Papaya seeds and AuNPs have potent antioxidant activity; moreover, the total phenolic contents are characterized. The data confirmed that the C. Papaya seed extract was a good bio-reductant way for AuNPs that can be applied as a promising field in different bio-applications.

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番木瓜种子植物化学、总酚和抗氧化活性评价及其在金纳米颗粒生物合成中的应用

利用绿色方法合成纳米颗粒并研究其性能是制药和生物医学产品领域研究的热点之一。本文以木瓜种子为还原剂和稳定剂，采用生态友好的途径合成纳米金。通过定性、定量和气相色谱-质谱分析，发现木瓜种子中含有多种化合物。确认了木瓜浓度、接触时间和温度对AuNPs的反应速率和形状的影响，并通过UV-Vis、AFM和SEM对生物合成的NPs进行了表征。AFM和SEM分析表明，该材料的粒径在40 ~ 105nm之间，平均直径为75.68nm，呈球形结构。采用TLC和DPPH分析研究了其抗氧化活性和自由基清除活性。结果表明，木瓜种子和AuNPs具有较强的抗氧化活性;此外，还对总酚含量进行了表征。结果表明，番木瓜种子提取物是一种较好的AuNPs生物还原剂，在不同的生物应用领域具有广阔的应用前景。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The Egyptian Journal of Chemistry

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