The Management of Hepatocellular Carcinoma at the Kara Teaching Hospital (Togo)

IF 1.7 4区医学 Q2 SURGERY

European Surgical Research Pub Date : 2022-06-30 DOI:10.33425/2689-1093.1041

Ossouvi Tamegnon, EL-HADJI Yakoubou, Rafiou, Adabra Komlan, Bouglouga Oumboma, Kanassoua Kokou, Kassegne Irokoura, D. David

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引用次数: 1

Abstract

Objective: To describe the epidemiological, diagnostic, therapeutic and evolutionary aspects of hepatocellular carcinoma at CHU Kara. Method: This is a retrospective study conducted over a period of 3 years in the Department of General Surgery and Hepato-Gastroenterology of CHU-Kara (Togo). Were included in our study all patients, aged over 15 years old hospitalized for hepatocellular carcinoma. Results: We recorded 98 cases out of 7237 hospitalized patients, i.e. a frequency of 1.4%. The patients were consisted of 65 men and 33 women with a sex ratio (F/M) of 0.5. The average age was 49 years old. Clinically, painful hepatomegaly was found in all cases; abdominal pain in all cases, poor general condition in 86 patients; collateral venous circulation in 3 cases. Alpha-fetoprotein (AFP) was above 400 ng/ml in all patients. Abdominal imaging revealed diffuse liver involvement in 85 patients (86.7%), a localized nodular appearance in 13 cases (13.3%).All these patients had received symptomatic treatment combining analgesics and antispasmodics. The mortality rate was 97.9% within 12 months. Conclusion: Hepatocellular carcinoma remains a serious condition and its diagnosis is often difficult. It poses a real problem of care in our developing countries.

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多哥卡拉教学医院肝细胞癌的治疗

目的:了解楚卡拉地区肝细胞癌的流行病学、诊断、治疗和演变情况。方法:这是一项为期3年的回顾性研究，在CHU-Kara(多哥)的普通外科和肝消化内科进行。我们的研究纳入了所有年龄在15岁以上因肝细胞癌住院的患者。结果:7237例住院患者中，我们记录了98例，即1.4%的频率。男性65例，女性33例，性别比(F/M)为0.5。平均年龄为49岁。临床均表现为肝肿大疼痛;所有病例腹痛，86例一般情况较差;侧支静脉循环3例。所有患者甲胎蛋白(AFP)均在400 ng/ml以上。腹部影像学显示85例(86.7%)患者肝脏弥漫性受累，13例(13.3%)患者出现局部结节。所有患者均给予镇痛和抗痉挛药物联合对症治疗。12个月内死亡率为97.9%。结论:肝细胞癌仍然是一种严重的疾病，其诊断往往很困难。这给发展中国家的医疗保健带来了真正的问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Surgical Research 医学-外科

CiteScore

2.30

自引率

6.20%

发文量

审稿时长

>12 weeks

期刊介绍： ''European Surgical Research'' features original clinical and experimental papers, condensed reviews of new knowledge relevant to surgical research, and short technical notes serving the information needs of investigators in various fields of operative medicine. Coverage includes surgery, surgical pathophysiology, drug usage, and new surgical techniques. Special consideration is given to information on the use of animal models, physiological and biological methods as well as biophysical measuring and recording systems. The journal is of particular value for workers interested in pathophysiologic concepts, new techniques and in how these can be introduced into clinical work or applied when critical decisions are made concerning the use of new procedures or drugs.