Vaccination for SARS-COV-2 in pregnancy in a referral center in Italy

Abstract

Objective The aim of the study was to investigate uptake of COVID-19 vaccination among pregnant women in a referral center in Italy. Methods This was an observational retrospective study conducted at ASL NA1 Centro, and at University of Naples Federico II, Italy, among pregnant women. The primary outcome was uptake of COVID-19 vaccination and its determinants. Results Data were available for 1,478 pregnant women who were offered COVID-19 vaccination during pregnancy. Of them, 498 (33.7%) rejected the vaccine, while 980 (66.3%) received at least 1 dose of the vaccine before delivery. Out of the 980 women who received vaccination, 357 (36.4%) were vaccinated in the second trimester, 497 (50.7%) in the third trimester, and 126 (12.9%) in the first trimester of pregnancy. 327 (33.3%) women received one dose of the vaccine in pregnancy, and 653 (66.6%) received two doses. Conclusion Of pregnant women eligible for COVID-19 vaccination, more than two-third cases accepted COVID-19 vaccination during pregnancy.