A Study of the Relation between Ocular Axial Length and Central Retinal Vein Occlusion at a Tertiary Care Hospital in Mumbai

Sailie Shirodkar, N. Shah
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Abstract

superficial deep intraretinal in all four of the retina associated variable of retinal venous engorgement and tortuosity, optic disc swelling, cotton wool ABSTRACT Aim: This study aims to assess the association between the ocular axial length (AL) and the pathogenesis of central retinal vein occlusion (CRVO) at a tertiary care hospital. Methods: This study included patients of unilateral CRVO. Informed consent was obtained, followed by comprehensive history taking, ophthalmic evaluation, systemic investigations as per protocol, and ocular investigations including OCT/FFA, depending on the requirement of the patient and duration of disease. Fifteen women and 15 men with a mean age of 64.98 years were selected. ALs of the affected (study group) and unaffected eye (control group) were measured by A-scan ultrasonography (US). Results: The mean AL of affected eyes in males was 23.0267 mm and that in unaffected eyes was 23.191 mm ( P = 0.000). The mean AL of affected eyes in females was 23.0131 mm and that in unaffected eyes was 23.030 mm ( P = 0.000). The ALs of affected eyes were shorter than those of unaffected eyes ( P = 0.000). These differences were statistically significant. The Cronbach’s α found is 0.925, which suggests a strong correlation between AL and CRVO. A comparison was also made between the ALs and CRVO based on the gender, and no statistical difference was found. Conclusion: Our study confirms the existence of shorter ALs in the affected eye of patients of CRVO on comparison with the unaffected eye. It also confirms that this difference is statistically significant in the total population and in each gender.
孟买一家三级医院眼轴长度与视网膜中央静脉阻塞关系的研究
摘要目的:本研究旨在评价某三级医院眼轴长度(AL)与视网膜中央静脉闭塞(CRVO)发病机制的关系。方法:本研究纳入单侧CRVO患者。获得知情同意后,根据患者的需要和病程,进行全面的病史记录、眼科评估、按方案进行系统检查,包括OCT/FFA等眼部检查。女性15人,男性15人,平均年龄64.98岁。采用a超扫描(US)测量受累眼(研究组)和未受累眼(对照组)的ALs。结果:男性患眼AL均值为23.0267 mm,未患眼AL均值为23.191 mm (P = 0.000)。女性患眼AL均值为23.0131 mm,未患眼AL均值为23.030 mm (P = 0.000)。病变眼的ALs短于正常眼(P = 0.000)。这些差异具有统计学意义。Cronbach’s α值为0.925,表明AL与CRVO之间存在较强的相关性。对ALs和CRVO进行性别比较,无统计学差异。结论:本研究证实了CRVO患者患眼与未患眼相比存在较短的ALs。它还证实,这种差异在总人口和每个性别中都具有统计学意义。
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