Depression in Older Adults - A Review

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-03-30 DOI:10.33425/2692-7918.1044

Ke Zhou, S. Tan, Shiela P Arroyo, Si Ching Lim

引用次数: 0

Abstract

The prevalence of major depressive disorder (MDD) is estimated to be 13.3%, while depressive symptoms are estimated to occur in 28.4% of older adults. A range of medical, functional, and psychosocial risk factors contribute to depression in this population. Depression in older adults may present differently than in younger adults with more physical complaints. Diagnosis becomes even more challenging in the presence of delirium and dementia, which often overlap in an older adult with MDD. It is important to assess suicide risks in older adults with depressive symptoms. Psychotherapy is recommended for mild to moderate depression, while antidepressants should be considered for severe depression or when psychotherapy is not available. Careful monitoring of side effects is important in older adults due to reduced physiological reserves.

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老年人抑郁症-综述

重度抑郁症(MDD)的患病率估计为13.3%，而抑郁症状估计发生在28.4%的老年人中。一系列的医疗、功能和社会心理风险因素导致了这一人群的抑郁症。老年人抑郁症的表现可能与年轻人不同，他们有更多的身体不适。在谵妄和痴呆的情况下，诊断变得更具挑战性，这在老年重度抑郁症患者中经常重叠。评估有抑郁症状的老年人的自杀风险很重要。轻度至中度抑郁症建议使用心理治疗，而重度抑郁症或心理治疗无效时应考虑使用抗抑郁药。由于生理储备减少，对老年人的副作用进行仔细监测很重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.