Yubin Zhou , Yuanyuan Wu , Oleksandr Pokholenko , Vladislav Papper , Robert S. Marks , Terry W.J. Steele
{"title":"Stilbene Switch Activated by Click Chemistry","authors":"Yubin Zhou , Yuanyuan Wu , Oleksandr Pokholenko , Vladislav Papper , Robert S. Marks , Terry W.J. Steele","doi":"10.1016/j.protcy.2017.04.006","DOIUrl":null,"url":null,"abstract":"<div><p>Stilbenes have not been widely regarded as fluorophore labels due to their difficulty in conjugation. Quenched fluorescence of maleimide functionalized stilbene is found to be restored after thiol binding, enabling separation-free fluorophore labelling.</p></div>","PeriodicalId":101042,"journal":{"name":"Procedia Technology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.protcy.2017.04.006","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Procedia Technology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212017317300075","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
Stilbenes have not been widely regarded as fluorophore labels due to their difficulty in conjugation. Quenched fluorescence of maleimide functionalized stilbene is found to be restored after thiol binding, enabling separation-free fluorophore labelling.