Infective Endocarditis Associated with Multisystem Inflammatory Syndrome in Children (MIS-C): Two Case Studies

IF 0.3 4区医学 Q4 ENGINEERING, BIOMEDICAL

IEEE Pulse Pub Date : 2023-06-14 DOI:10.3329/pulse.v14i1-3.66894

T. Nazrin, M. Hassan

{"title":"Infective Endocarditis Associated with Multisystem Inflammatory Syndrome in Children (MIS-C): Two Case Studies","authors":"T. Nazrin, M. Hassan","doi":"10.3329/pulse.v14i1-3.66894","DOIUrl":null,"url":null,"abstract":"Infective endocarditis (IE) is the infection of endocardial surface of the heart. IE is the rare disease with significant complications which require early diagnosis and proper treatment for reducing morbidity and mortality.IE with vegetation on pulmonary valve, leaflets are uncommon. However, we have diagnosed one case with infective endocarditis associated with Multisystem Inflammatory Syndrome in Children (MIS-C) which is related with COVID-19. MIS-C is commonly associated with coronary artery aneurysm (CAA), myocarditis and heart failure. Our patient had IE and was subsequently affected with MIS-C due to COVID. The child had vegetation on pulmonary valve with flail pulmonary valve-leaflet with grade II pulmonary regurgitation and MIS-C related CAA. The second child was previously diagnosed as infective endocarditis and was treated in other hospital for intravenous antibiotic for four weeks. However, in our hospital he was diagnosed clinically, by laboratory investigations and by echocardiography as MIS-C with large vegetation, which was surgically removed, and biopsy revealed mycobacterium tuberculosis as causative organism. \nPulse Volume 12-14 2020-2022 p.26-31","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":null,"pages":null},"PeriodicalIF":0.3000,"publicationDate":"2023-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Pulse","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.3329/pulse.v14i1-3.66894","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}

引用次数: 0

Abstract

Infective endocarditis (IE) is the infection of endocardial surface of the heart. IE is the rare disease with significant complications which require early diagnosis and proper treatment for reducing morbidity and mortality.IE with vegetation on pulmonary valve, leaflets are uncommon. However, we have diagnosed one case with infective endocarditis associated with Multisystem Inflammatory Syndrome in Children (MIS-C) which is related with COVID-19. MIS-C is commonly associated with coronary artery aneurysm (CAA), myocarditis and heart failure. Our patient had IE and was subsequently affected with MIS-C due to COVID. The child had vegetation on pulmonary valve with flail pulmonary valve-leaflet with grade II pulmonary regurgitation and MIS-C related CAA. The second child was previously diagnosed as infective endocarditis and was treated in other hospital for intravenous antibiotic for four weeks. However, in our hospital he was diagnosed clinically, by laboratory investigations and by echocardiography as MIS-C with large vegetation, which was surgically removed, and biopsy revealed mycobacterium tuberculosis as causative organism. Pulse Volume 12-14 2020-2022 p.26-31

查看原文本刊更多论文

儿童感染性心内膜炎与多系统炎症综合征(MIS-C):两个案例研究

感染性心内膜炎(IE)是指心脏的心内膜表面感染。IE是一种罕见的疾病，有明显的并发症，需要早期诊断和适当治疗，以降低发病率和死亡率。肺瓣上有植被的IE，小叶少见。然而，我们诊断出1例与COVID-19相关的儿童多系统炎症综合征(misc)相关的感染性心内膜炎。misc通常与冠状动脉瘤(CAA)、心肌炎和心力衰竭有关。我们的患者患有IE，随后因COVID而感染了misc。患儿肺动脉瓣赘生物伴连枷型肺动脉瓣-小叶伴II级肺返流及misc相关CAA。第二个孩子之前被诊断为感染性心内膜炎，在其他医院静脉注射抗生素治疗了四周。然而，在我们医院，通过临床、实验室检查和超声心动图诊断为misc伴大植被，手术切除，活检显示结核分枝杆菌为病原生物。脉冲卷12-14 2020-2022页26-31

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

IEEE Pulse ENGINEERING, BIOMEDICAL-

CiteScore

1.10

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： IEEE Pulse covers both general and technical articles on current technologies and methods used in biomedical and clinical engineering; societal implications of medical technologies; current news items; book reviews; patent descriptions; and correspondence. Special interest departments, students, law, clinical engineering, ethics, new products, society news, historical features and government.