Frequency of Influenza-A-H1N1 in Patients with Community-Acquired Pneumonia Admitted to Loghman Hakim Hospital

H. Mortazavi, M. Shabani, Mobina Ghasemi, Maryam Haghighi-Morad, Nastaran Payandeh, S. Monavari, Dovod Javanmard, L. Gachkar, Behjat Barari, A. Pajoumand
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Abstract

Background: Here we assessed the incidence of Influenza-A-H1N1-related pneumonia in community-acquired pneumonia (CAP) at Loghman Hakim Hospital, Tehran, Iran. M aterials and Methods: In this prospective study from November 22, 2016, to June 21, 2017, patients with CAP and suspected to seasonal influenza were included. Rapid Antigen test and quantitative real-time PCR assay were performed on samples. P-value < 0.05 was considered significant. In addition, radiologic patterns of them were evaluated. R es ults: a total of 29 admitted CAP patients were suspected of seasonal influenza. Two cases out of them were positive for influenza by real-time PCR, similar to result of influenza rapid test. The most common finding in their chest X ray was consolidation in one lobe. None of them vaccinated against influenza. Only nine patients received empiric Oseltamivir treatment. The amount of irrational antibiotic administration was significant. C onclusion: Despite low statistical numbers, admitted influenza CAP patients did not have unusual symptoms and radiologic patterns. Other results in this study showed need for antibiotic stewardship program and better training about necessity of vaccination.
Loghman Hakim医院收治的社区获得性肺炎患者甲型h1n1流感的频率
背景:在这里,我们评估了伊朗德黑兰Loghman Hakim医院社区获得性肺炎(CAP)中甲型h1n1流感相关肺炎的发病率。材料与方法:在2016年11月22日至2017年6月21日的前瞻性研究中,纳入了CAP和疑似季节性流感患者。对样品进行快速抗原检测和实时荧光定量PCR检测。p值< 0.05为显著性。并对其影像学表现进行评价。结果:29例CAP住院患者疑似季节性流感。其中2例实时荧光定量PCR阳性,与流感快速检测结果相似。胸部X光最常见的发现是单叶实变。他们中没有人接种过流感疫苗。只有9名患者接受了经验性奥司他韦治疗。不合理给药数量显著。结论:尽管统计数字低,入院的流感CAP患者没有异常症状和放射学模式。本研究的其他结果表明需要抗生素管理计划和更好的疫苗接种必要性培训。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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