Coalescence of Traditional Medicine Methods and System Biology Approaches Should Occur to Uncover the Molecular Basis of Remedies for Childhood Pneumonia

R. Chakraborty
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Abstract

The treatment decisions in children with pneumonia depend on the age, clinical status, and probable etiology of the infectious agent. There are several age-old practices for healing childhood pneumonia. Homeopathic remedies for pneumonia are also known. Several herbs and plant parts have usages in treating pneumonia. From the treasure trove of several dispersed-unsynchronized scientific studies and ethno-knowledge, it emerges that synergistic formulation based on plant and animal ingredients are highly effective in the treatment and prophylaxis of pneumonia among children. These practices have undergone several human trials as it bear centuries-old tradition. Hence, multi-component therapy may provide revived medication(s) to save millions of children dying every year due to pneumonia with the rider that it has to be validated and scientifically scrutinized for multiple perturbations of biological networks, in addition to multiple targets with system biology tools, now available, to establish the basis of multi-component therapy.
传统医学方法与系统生物学方法的结合应揭示儿童肺炎治疗的分子基础
肺炎患儿的治疗决定取决于年龄、临床状况和感染源的可能病因。治疗儿童肺炎有几种古老的做法。顺势疗法治疗肺炎也是众所周知的。几种草药和植物部位对治疗肺炎有疗效。从几项分散的、不同步的科学研究和民族知识的宝库中,我们发现,以植物和动物成分为基础的协同配方在治疗和预防儿童肺炎方面非常有效。这些做法经历了几次人体试验,因为它具有几个世纪的传统。因此,多组分治疗可以提供复活药物,以挽救每年因肺炎而死亡的数百万儿童,但附加条件是,除了使用现有的系统生物学工具进行多靶点治疗外,还必须对生物网络的多重扰动进行验证和科学审查,以建立多组分治疗的基础。
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