Treatment of Severe Urinary Incontinence following Radical Prostatectomy: Experience with Bioceram as a Bulking Agent

M. Ayati, E. Amini, M. Nowroozi, Seyed Ali Momeni, S. O. Moghadam, R. S. Damavand
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引用次数: 0

Abstract

Background: To evaluate the efficacy of Bioceram injection in men with severe stress urinary incontinence following radical prostatectomy. Methods: A total of 18 patients underwent retrograde injection of Bioceram for severe stress urinary incontinence following radical prostatectomy. Evaluation by pad test, international consultation on the Incontinence Questionnaire - Short Form (ICIQ-SF) and American Urology Association Symptom Score - Quality of Life (AUASS-QOL) was performed before and after injection therapy. Patients were considered cured if they were using no pads or only one safety pad per day. Results: Of 18 patients, 14 had received postoperative external beam radiation therapy. Furthermore, 5 patients required transurethral incision due to simultaneous stricture of the urethrovesical anastomosis. The baseline daily pad count changed from a mean of 6.1± 0.8 to 5.3 ± 1.7 (p = 0.010). None of the patients were cured and only 3 patients showed signs of improvement following injection. Conclusion: In patients with severe urinary incontinence, treatment with bulking agent injection is associated with modest efficacy.
根治性前列腺切除术后严重尿失禁的治疗:生物胶作为膨胀剂的经验
背景:评价生物角蛋白注射液治疗根治性前列腺切除术后严重压力性尿失禁的疗效。方法:对18例根治性前列腺切除术后严重应激性尿失禁患者行生物角胺逆行注射治疗。在注射治疗前后通过尿垫试验、国际失禁问卷短表(ICIQ-SF)和美国泌尿学会症状评分-生活质量(AUASS-QOL)进行评估。如果患者不使用护垫或每天只使用一个安全护垫,则认为他们已经治愈。结果:18例患者中,14例接受了术后外束放射治疗。5例患者因尿道膀胱吻合术同时狭窄,需经尿道切开。基线每日尿垫计数从平均值6.1±0.8变为5.3±1.7 (p = 0.010)。所有患者均未治愈,仅有3例患者在注射后出现好转迹象。结论:对于严重尿失禁患者,注射填充剂治疗效果一般。
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