Pediatric intoxication inducing after dental pain management OTC Benzocaine product.

DR. MUHI.N. Salman
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引用次数: 1

Abstract

Background; Methemoglobinemia is a rare disorder of the blood in which there is an increase in the proportion of hemoglobin present in the oxidized form (methemoglobin). It may be inherited, due either to a deficiency of methemoglobin reductase or to a structural abnormality of hemoglobin, or it may be acquired, usually secondary to exposure to drugs or chemicals that oxidize hemoglobin l. Administration of some local anesthetics such as benzocaine at large doses may lead to an acute effect of risk Methemoglobinemia.. Presentation ; A 6-years-old child was suffering from dyspnea, headache, and grayish in appearance. The patient was self-treating with an over-the-counter topical oral benzocaine. Treatment; The diagnosis of methemoglobinemia was made in conjunction with consultation with a medical toxicologist and treatment with oxygen and methylene blue as antidote was given 1mg/kg of 1% solution intravenously over 7minutes. The symptoms improved within 30 minutes and child felt markedly better within 1.5 hour. Conclusion; Methylene blue is the specific antidote, but should be reserved for more severe cases.
小儿中毒诱导后牙痛处理非处方苯佐卡因产品。
背景;高铁血红蛋白血症是一种罕见的血液疾病,其中以氧化形式(高铁血红蛋白)存在的血红蛋白比例增加。由于缺乏高铁血红蛋白还原酶或血红蛋白结构异常,它可能是遗传的,也可能是获得性的,通常是由于暴露于氧化血红蛋白的药物或化学物质所致。大剂量使用局部麻醉剂,如苯佐卡因,可导致高铁血红蛋白血症的急性反应。6岁儿童,呼吸困难,头痛,面色发灰。患者使用非处方局部口服苯佐卡因进行自我治疗。高铁血红蛋白血症的诊断是在咨询医学毒理学家的同时做出的,并在7分钟内静脉给予氧和亚甲基蓝作为解毒剂1mg/kg的1%溶液。患儿症状在30分钟内改善,1.5小时内感觉明显好转。亚甲基蓝是一种特殊的解毒剂,但应保留用于更严重的病例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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