Parkinson’s Disease: What is New?

Abstract

motor and non-motor clinical features are Table 1. Literature now suggests three different stages in clinical evolution of a patient with PD as depicted Table 2 and it is important to appreciate the first two stages. A new subcategory of ‘clinico-genetic PD’ has been added recently. ABSTRACT Parkinson disease (PD) is one of the most common movement disorders in elderly population worldwide. It is a complex, progressive neurodegenerative disease with a constellation of heterogeneous motor and non-motor clinical features. Research developments in recent years have made remarkable progress in pathophysiology, diagnosis, and treatment of this disease. We wish to highlight these recent developments that have the potential to change the management of PD in routine clinical practice in near future. This manuscript will discuss the current developments in the diagnosis, pathophysiology and particularly, the treatment aspects of this commonly encountered disease.