Positive Bacterial Culture among Lower Respiratory Tract Specimens of Patients in a Tertiary Care Centre: A Descriptive Cross-sectional Study.

IF 1.2 4区教育学 Q2 EDUCATION & EDUCATIONAL RESEARCH

Literacy Pub Date : 2022-04-15 DOI:10.31729/jnma.7219

Shusila Khadka, Achut Barakoti, Ram Prasad Adhikari, Laxmi Kant Khanal, Jyotshna Sapkota

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引用次数: 0

Abstract

Introduction: Lower respiratory tract infection accounts for a great burden of disease worldwide. The problem has further increased due to increasing antimicrobial resistance. This study was done to find out prevalence of positive bacterial culture among lower respiratory tract specimens of patients in a tertiary care centre.

Methods: A descriptive cross-sectional study was done in the Laboratory of Clinical Microbiology in a tertiary care centre from May, 2021 to October, 2021. Ethical approval was received from the Institutional Review Committee (Reference number: 045-077/078). A total of 635 specimens were collected by convenience sampling. The specimens were cultured as per standard microbiological techniques. Antibiotic susceptibility was performed following Clinical and Laboratory Standards Institute (2020) guidelines. Microsoft Excel was used for data entry and analysis. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion.

Results: Among the 635 lower respiratory specimens, 112 (17.63%) (111.97 to 112.03 at 95% Confidence Interval) showed positive bacterial culture. Klebsiella pneumoniae 44 (37.93%) was the commonest isolate followed by Acinetobacter calcoaceticus baumannii complex 34 (29.31%).

Conclusions: The prevalence of positive bacterial culture among lower respiratory specimens was lower when compared to other studies done in similar settings.

Keywords: antibiotic resistance; gram negative bacteria; respiratory tract infections.

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一家三级医疗中心患者下呼吸道标本中的阳性细菌培养：一项描述性横断面研究。

导言：下呼吸道感染是全世界的一大疾病负担。由于抗菌药耐药性的增加，这一问题进一步加剧。本研究旨在了解一家三级医疗中心患者下呼吸道标本中细菌培养阳性的发生率：方法：2021 年 5 月至 2021 年 10 月，在一家三级医疗中心的临床微生物实验室进行了一项描述性横断面研究。研究获得了机构审查委员会的伦理批准（参考编号：045-077/078）。研究人员通过方便抽样的方式共收集了 635 份标本。标本按照标准微生物学技术进行培养。抗生素药敏试验按照临床和实验室标准研究所（2020 年）指南进行。数据输入和分析使用 Microsoft Excel。计算了95%置信区间的点估计值以及频率和比例：在 635 份下呼吸道标本中，112 份（17.63%）（95% 置信区间为 111.97 至 112.03）细菌培养呈阳性。肺炎克雷伯菌（Klebsiella pneumoniae）44 株（37.93%）是最常见的分离菌，其次是鲍曼不动杆菌（Acinetobacter calcoaceticus baumannii complex）34 株（29.31%）：关键词：抗生素耐药性；革兰氏阴性菌；呼吸道感染。

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来源期刊

Literacy Multiple-

CiteScore

3.00

自引率

7.70%

发文量

期刊介绍： Literacy is the official journal of the United Kingdom Literacy Association (formerly the United Kingdom Reading Association), the professional association for teachers of literacy. Literacy is a refereed journal for those interested in the study and development of literacy. Its readership comprises practitioners, teacher educators, researchers and both undergraduate and graduate students. Literacy offers educators a forum for debate through scrutinising research evidence, reflecting on analysed accounts of innovative practice and examining recent policy developments.