Minimally Invasive Methods for Staging in Lung Cancer: Systematic Review and Meta-Analysis.

IF 3.7 2区 计算机科学 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC
IEEE Antennas and Wireless Propagation Letters Pub Date : 2016-01-01 Epub Date: 2016-10-13 DOI:10.1155/2016/1024709
Gonzalo Labarca, Carlos Aravena, Francisco Ortega, Alex Arenas, Adnan Majid, Erik Folch, Hiren J Mehta, Michael A Jantz, Sebastian Fernandez-Bussy
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引用次数: 0

Abstract

Introduction. Endobronchial ultrasound (EBUS) is a procedure that provides access to the mediastinal staging; however, EBUS cannot be used to stage all of the nodes in the mediastinum. In these cases, endoscopic ultrasound (EUS) is used for complete staging. Objective. To provide a synthesis of the evidence on the diagnostic performance of EBUS + EUS in patients undergoing mediastinal staging. Methods. Systematic review and meta-analysis to evaluate the diagnostic yield of EBUS + EUS compared with surgical staging. Two researchers performed the literature search, quality assessments, data extractions, and analyses. We produced a meta-analysis including sensitivity, specificity, and likelihood ratio analysis. Results. Twelve primary studies (1515 patients) were included; two were randomized controlled trials (RCTs) and ten were prospective trials. The pooled sensitivity for combined EBUS + EUS was 87% (CI 84-89%) and the specificity was 99% (CI 98-100%). For EBUS + EUS performed with a single bronchoscope group, the sensitivity improved to 88% (CI 83.1-91.4%) and specificity improved to 100% (CI 99-100%). Conclusion. EBUS + EUS is a highly accurate and safe procedure. The combined procedure should be considered in selected patients with lymphadenopathy noted at stations that are not traditionally accessible with conventional EBUS.

肺癌分期的微创方法:系统综述与元分析》。
简介。支气管内超声检查(EBUS)是一种可对纵隔进行分期的检查方法,但 EBUS 无法对纵隔内的所有结节进行分期。在这种情况下,可使用内窥镜超声(EUS)进行全面分期。目的。对接受纵隔分期的患者使用 EBUS + EUS 的诊断效果进行证据综述。方法。进行系统回顾和荟萃分析,评估 EBUS + EUS 与手术分期相比的诊断率。两名研究人员进行了文献检索、质量评估、数据提取和分析。我们进行了荟萃分析,包括敏感性、特异性和似然比分析。结果。共纳入了 12 项主要研究(1515 名患者);其中 2 项为随机对照试验 (RCT),10 项为前瞻性试验。合并 EBUS + EUS 的汇总敏感性为 87%(CI 84-89%),特异性为 99%(CI 98-100%)。对于使用单一支气管镜的 EBUS + EUS 组,敏感性提高到 88% (CI83.1-91.4%),特异性提高到 100% (CI99-100%)。结论EBUS + EUS 是一种高度准确和安全的手术。对于传统 EBUS 无法到达的淋巴结病变部位,有选择性的患者应考虑采用联合手术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
8.00
自引率
9.50%
发文量
529
审稿时长
1.0 months
期刊介绍: IEEE Antennas and Wireless Propagation Letters (AWP Letters) is devoted to the rapid electronic publication of short manuscripts in the technical areas of Antennas and Wireless Propagation. These are areas of competence for the IEEE Antennas and Propagation Society (AP-S). AWPL aims to be one of the "fastest" journals among IEEE publications. This means that for papers that are eventually accepted, it is intended that an author may expect his or her paper to appear in IEEE Xplore, on average, around two months after submission.
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