Prevalence of depression, cognition impairment, nutrition and related factors in patients with chronic kidney disease stage 3 - 5

The South Dakota journal of medicine and pharmacy Pub Date : 2022-11-01 DOI:10.34071/jmp.2022.6.7

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Abstract

Introduction: Chronic kidney disease (CKD) affects mental health, cognition and nutrition. Objectives: (1) To determine the prevalence of depression, cognition impairment and nutrition in patients with CKD stage 3-5. (2) To explore the relationship between depression and cognitive disorders, nutritional disorders, and some characteristics in patients with CKD stage 3-5. Methodology: cross-sectional description on 433 patients with chronic kidney disease stage 3-5. Corresponding tools for assessing screening for depression, cognitive decline, and nutritional status are Beck Depression Inventory (BDI), the Mini Mental State Examination (MMSE), and the Mini Nutritional Assessment (MNA). Results: (1) The rate of depression, cognition impairment and malnutrition risk was 40.9%, 20.3%; 50.1% respectively. (2) Patients with CKD who were at risk of malnutrition and cognitive disorders were more likely to suffer from depression than patients with normal nutritional status and cognitive status. Conclusion: Depression is quite common in patients with chronic kidney disease stage 3 - 5, screening is needed in these patients. There is a positive relationship between depression and the risk of malnutrition, the level of cognitive dysfunction in patients with CKD stage 3 - 5. Key words: Chronic kidney disease, depression, cognitive disorders, nutrition status, prevalence, relevance.

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慢性肾病3 - 5期患者抑郁、认知障碍、营养及相关因素的患病率

慢性肾脏疾病(CKD)影响心理健康、认知和营养。目的:(1)了解CKD 3-5期患者抑郁、认知功能障碍和营养状况的患病率。(2)探讨3-5期CKD患者抑郁与认知障碍、营养障碍及某些特征的关系。方法:对433例慢性肾脏疾病3-5期患者进行横断面描述。相应的评估抑郁筛查、认知能力下降和营养状况的工具是贝克抑郁量表(BDI)、迷你精神状态检查(MMSE)和迷你营养评估(MNA)。结果:(1)抑郁、认知障碍和营养不良发生率分别为40.9%、20.3%;50.1%。(2)存在营养不良和认知障碍风险的CKD患者比营养状况和认知状况正常的患者更容易发生抑郁。结论:慢性肾脏病3 ~ 5期患者抑郁发生率较高，需要对其进行筛查。慢性肾病3 - 5期患者的营养不良风险、认知功能障碍水平与抑郁呈正相关。关键词:慢性肾病，抑郁症，认知障碍，营养状况，患病率，相关性

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The South Dakota journal of medicine and pharmacy

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