Formulation and Physical Characterization of Sunflower Oil Nano Emulsion Containing Cinnamon Bark Extract

Sani Ega Priani, Sri Peni Fitrianingsih, Livia Syafnir
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Abstract

This research developed a sunflower oil nano emulsion containing cinnamon bark extract. Cinnamon bark contains many bioactive compounds that provide various pharmacological benefits, including antioxidant properties. The bark extract, when developed into a nano emulsion system using sunflower oil, improves the antioxidant property. The maceration method using ethanol 95% was used to extract the cinnamon bark and then further developed into the nano emulsion system using between 80 as surfactant and PEG 400 as cosurfactant. The optimum nano emulsion formula contains 4% sunflower oil, and 30% PEG 400. The sunflower oil nano emulsion is transparent, with a globule size of 102 ± 32 nm. The optimum formula of cinnamon bark nano emulsion was achieved with 0.25% extract. This shows good physical characteristics and stability. Keywords: nanoemulsion, cinnamon bark, sunflower oil
肉桂皮提取物向日葵油纳米乳液的配方及物理特性研究
本研究开发了一种含有肉桂皮提取物的葵花籽油纳米乳液。肉桂皮含有许多生物活性化合物,提供各种药理益处,包括抗氧化特性。将树皮提取物用葵花籽油制成纳米乳液体系,提高了抗氧化性能。采用95%乙醇浸渍法提取肉桂皮,以80为表面活性剂,peg400为助表面活性剂,进一步发展成纳米乳液体系。最佳的纳米乳液配方含有4%葵花籽油和30% peg400。葵花籽油纳米乳液透明,粒径为102±32 nm。以0.25%的提取率获得肉桂皮纳米乳液的最佳配方。这显示了良好的物理特性和稳定性。关键词:纳米乳液,桂皮,葵花籽油
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